Literature DB >> 25301715

AWARE-AWAreness during REsuscitation-a prospective study.

Sam Parnia1, Ken Spearpoint2, Gabriele de Vos3, Peter Fenwick4, Diana Goldberg5, Jie Yang5, Jiawen Zhu5, Katie Baker4, Hayley Killingback6, Paula McLean7, Melanie Wood7, A Maziar Zafari8, Neal Dickert8, Roland Beisteiner9, Fritz Sterz9, Michael Berger9, Celia Warlow10, Siobhan Bullock10, Salli Lovett11, Russell Metcalfe Smith McPara12, Sandra Marti-Navarette13, Pam Cushing14, Paul Wills15, Kayla Harris4, Jenny Sutton16, Anthony Walmsley17, Charles D Deakin4, Paul Little4, Mark Farber18, Bruce Greyson19, Elinor R Schoenfeld5.   

Abstract

BACKGROUND: Cardiac arrest (CA) survivors experience cognitive deficits including post-traumatic stress disorder (PTSD). It is unclear whether these are related to cognitive/mental experiences and awareness during CPR. Despite anecdotal reports the broad range of cognitive/mental experiences and awareness associated with CPR has not been systematically studied.
METHODS: The incidence and validity of awareness together with the range, characteristics and themes relating to memories/cognitive processes during CA was investigated through a 4 year multi-center observational study using a three stage quantitative and qualitative interview system. The feasibility of objectively testing the accuracy of claims of visual and auditory awareness was examined using specific tests. The outcome measures were (1) awareness/memories during CA and (2) objective verification of claims of awareness using specific tests.
RESULTS: Among 2060 CA events, 140 survivors completed stage 1 interviews, while 101 of 140 patients completed stage 2 interviews. 46% had memories with 7 major cognitive themes: fear; animals/plants; bright light; violence/persecution; deja-vu; family; recalling events post-CA and 9% had NDEs, while 2% described awareness with explicit recall of 'seeing' and 'hearing' actual events related to their resuscitation. One had a verifiable period of conscious awareness during which time cerebral function was not expected.
CONCLUSIONS: CA survivors commonly experience a broad range of cognitive themes, with 2% exhibiting full awareness. This supports other recent studies that have indicated consciousness may be present despite clinically undetectable consciousness. This together with fearful experiences may contribute to PTSD and other cognitive deficits post CA.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Awareness; Cardiac arrest; Consciousness; Explicit memory; Implicit memory; Near death experiences; Out of body experiences; Post traumatic stress disorder

Mesh:

Year:  2014        PMID: 25301715     DOI: 10.1016/j.resuscitation.2014.09.004

Source DB:  PubMed          Journal:  Resuscitation        ISSN: 0300-9572            Impact factor:   5.262


  19 in total

1.  Asphyxia-activated corticocardiac signaling accelerates onset of cardiac arrest.

Authors:  Duan Li; Omar S Mabrouk; Tiecheng Liu; Fangyun Tian; Gang Xu; Santiago Rengifo; Sarah J Choi; Abhay Mathur; Charles P Crooks; Robert T Kennedy; Michael M Wang; Hamid Ghanbari; Jimo Borjigin
Journal:  Proc Natl Acad Sci U S A       Date:  2015-04-06       Impact factor: 11.205

Review 2.  Semiology and Mechanisms of Near-Death Experiences.

Authors:  Costanza Peinkhofer; Jens P Dreier; Daniel Kondziella
Journal:  Curr Neurol Neurosci Rep       Date:  2019-07-27       Impact factor: 5.081

Review 3.  [Interaction between heart and brain in sudden cardiac death].

Authors:  M Fatar; I Akin; M Borggrefe; M Platten; A Alonso
Journal:  Herz       Date:  2017-04       Impact factor: 1.443

4.  Consciousness with cardiopulmonary resuscitation.

Authors:  Roger Gray
Journal:  Can Fam Physician       Date:  2018-07       Impact factor: 3.275

5.  2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group.

Authors:  Myra H Wyckoff; Eunice M Singletary; Jasmeet Soar; Theresa M Olasveengen; Robert Greif; Helen G Liley; David Zideman; Farhan Bhanji; Lars W Andersen; Suzanne R Avis; Khalid Aziz; Jason C Bendall; David C Berry; Vere Borra; Bernd W Böttiger; Richard Bradley; Janet E Bray; Jan Breckwoldt; Jestin N Carlson; Pascal Cassan; Maaret Castrén; Wei-Tien Chang; Nathan P Charlton; Adam Cheng; Sung Phil Chung; Julie Considine; Daniela T Costa-Nobre; Keith Couper; Katie N Dainty; Peter G Davis; Maria Fernanda de Almeida; Allan R de Caen; Edison F de Paiva; Charles D Deakin; Therese Djärv; Matthew J Douma; Ian R Drennan; Jonathan P Duff; Kathryn J Eastwood; Walid El-Naggar; Jonathan L Epstein; Raffo Escalante; Jorge G Fabres; Joe Fawke; Judith C Finn; Elizabeth E Foglia; Fredrik Folke; Karoline Freeman; Elaine Gilfoyle; Craig A Goolsby; Amy Grove; Ruth Guinsburg; Tetsuo Hatanaka; Mary Fran Hazinski; George S Heriot; Karen G Hirsch; Mathias J Holmberg; Shigeharu Hosono; Ming-Ju Hsieh; Kevin K C Hung; Cindy H Hsu; Takanari Ikeyama; Tetsuya Isayama; Vishal S Kapadia; Mandira Daripa Kawakami; Han-Suk Kim; David A Kloeck; Peter J Kudenchuk; Anthony T Lagina; Kasper G Lauridsen; Eric J Lavonas; Andrew S Lockey; Carolina Malta Hansen; David Markenson; Tasuku Matsuyama; Christopher J D McKinlay; Amin Mehrabian; Raina M Merchant; Daniel Meyran; Peter T Morley; Laurie J Morrison; Kevin J Nation; Michael Nemeth; Robert W Neumar; Tonia Nicholson; Susan Niermeyer; Nikolaos Nikolaou; Chika Nishiyama; Brian J O'Neil; Aaron M Orkin; Osokogu Osemeke; Michael J Parr; Catherine Patocka; Jeffrey L Pellegrino; Gavin D Perkins; Jeffrey M Perlman; Yacov Rabi; Joshua C Reynolds; Giuseppe Ristagno; Charles C Roehr; Tetsuya Sakamoto; Claudio Sandroni; Taylor Sawyer; Georg M Schmölzer; Sebastian Schnaubelt; Federico Semeraro; Markus B Skrifvars; Christopher M Smith; Michael A Smyth; Roger F Soll; Takahiro Sugiura; Sian Taylor-Phillips; Daniele Trevisanuto; Christian Vaillancourt; Tzong-Luen Wang; Gary M Weiner; Michelle Welsford; Jane Wigginton; Jonathan P Wyllie; Joyce Yeung; Jerry P Nolan; Katherine M Berg
Journal:  Resuscitation       Date:  2021-11-11       Impact factor: 5.262

6.  Anomalous Experiences, Trauma, and Symbolization Processes at the Frontiers between Psychoanalysis and Cognitive Neurosciences.

Authors:  Thomas Rabeyron; Tianna Loose
Journal:  Front Psychol       Date:  2015-12-21

7.  Is It Possible to Maintain Consciousness and Spontaneous Ventilation with Chest Compression in the Early Phase of Cardiac Arrest?

Authors:  Menekse Oksar; Selim Turhanoglu
Journal:  Case Rep Anesthesiol       Date:  2016-02-11

8.  Neuroscience and Brain Death Controversies: The Elephant in the Room.

Authors:  Joseph L Verheijde; Mohamed Y Rady; Michael Potts
Journal:  J Relig Health       Date:  2018-10

9.  Cardiac arrest teams perspectives on communication and ethical conflicts related to awareness during CPR, a focus group study protocol.

Authors:  Rune Sarauw Lundsgaard; Kristine Sarauw Lundsgaard
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2018-09-27       Impact factor: 2.953

10.  The mind-body Cartesian dualism and psychiatry.

Authors:  Florence Thibaut
Journal:  Dialogues Clin Neurosci       Date:  2018-03       Impact factor: 5.986

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