Literature DB >> 25300776

Multitasking in Gonadotropin-Releasing Hormone Neuron Dendrites.

Karl J Iremonger1, Allan E Herbison.   

Abstract

Gonadotropin-releasing hormone (GnRH) neurons integrate synaptic information in their dendrites in order to precisely control GnRH secretion and hence fertility. Recent discoveries concerning the structure and function of GnRH neuron dendrites have shed new light on the control of GnRH neuron excitability and GnRH secretion. This work suggests that GnRH neurons have a unique projection to the median eminence that possesses both dendritic and axonal properties. We propose that this 'dendron' projection allows GnRH neurons to multitask and integrate information in ways that would not be possible in a classically envisioned axon projection.
© 2014 S. Karger AG, Basel.

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Year:  2014        PMID: 25300776     DOI: 10.1159/000368364

Source DB:  PubMed          Journal:  Neuroendocrinology        ISSN: 0028-3835            Impact factor:   4.914


  8 in total

1.  Time-of-day-dependent sensitivity of the reproductive axis to RFamide-related peptide-3 inhibition in female Syrian hamsters.

Authors:  Neta Gotlieb; Cydni N Baker; Jacob Moeller; Lance J Kriegsfeld
Journal:  J Neuroendocrinol       Date:  2019-11       Impact factor: 3.627

2.  Spike and Neuropeptide-Dependent Mechanisms Control GnRH Neuron Nerve Terminal Ca2+ over Diverse Time Scales.

Authors:  Karl J Iremonger; Robert Porteous; Allan E Herbison
Journal:  J Neurosci       Date:  2017-02-24       Impact factor: 6.167

3.  Optogenetic activation of GnRH neurons reveals minimal requirements for pulsatile luteinizing hormone secretion.

Authors:  Pauline Campos; Allan E Herbison
Journal:  Proc Natl Acad Sci U S A       Date:  2014-12-08       Impact factor: 11.205

4.  A synthetic kisspeptin analog that triggers ovulation and advances puberty.

Authors:  C Decourt; V Robert; K Anger; M Galibert; J-B Madinier; X Liu; H Dardente; D Lomet; A F Delmas; A Caraty; A E Herbison; G M Anderson; V Aucagne; M Beltramo
Journal:  Sci Rep       Date:  2016-06-01       Impact factor: 4.379

5.  Diversity of Axonal and Dendritic Contributions to Neuronal Output.

Authors:  Jean-Marc Goaillard; Estelle Moubarak; Mónica Tapia; Fabien Tell
Journal:  Front Cell Neurosci       Date:  2020-01-22       Impact factor: 5.505

Review 6.  Timing the Juvenile-Adult Neurohormonal Transition: Functions and Evolution.

Authors:  Celia G Barredo; Beatriz Gil-Marti; Derya Deveci; Nuria M Romero; Francisco A Martin
Journal:  Front Endocrinol (Lausanne)       Date:  2021-02-12       Impact factor: 5.555

7.  Electrophysiology of Hypothalamic Magnocellular Neurons In vitro: A Rhythmic Drive in Organotypic Cultures and Acute Slices.

Authors:  Jean-Marc Israel; Stéphane H Oliet; Philippe Ciofi
Journal:  Front Neurosci       Date:  2016-03-31       Impact factor: 4.677

Review 8.  Neuronal sub-compartmentalization: a strategy to optimize neuronal function.

Authors:  Alessandra Donato; Konstantinos Kagias; Yun Zhang; Massimo A Hilliard
Journal:  Biol Rev Camb Philos Soc       Date:  2019-01-04
  8 in total

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