AIMS: To describe a cohort of new opioid users (adult noncancer patients) in terms of clinical characteristics and treatment patterns in the UK and Germany. MATERIAL & METHODS: Data used were extracted from electronic medical records databases (UK: Clinical Practice Research Database-Hospital Episode Statistics; Germany: IMS Disease Analyzer) covering the 2008-2012 period. RESULTS: Most eligible patients were treated with opioids for less than 6 months (UK: 78.7% and Germany: 93.7%) and indexed on weak opioids (UK: 89.5% and Germany: 88.6%). Most prescribed opioids were codeine (UK) and tramadol (Germany). Most prevalent comorbidities were dorsalgia/depression. Constipation was observed in 16.8%/17.4% (UK/Germany) of chronic users (>6 months). CONCLUSION: While both populations were highly morbid populations largely initiated on weak opioids, chronic use was less common in Germany.
AIMS: To describe a cohort of new opioid users (adult noncancer patients) in terms of clinical characteristics and treatment patterns in the UK and Germany. MATERIAL & METHODS: Data used were extracted from electronic medical records databases (UK: Clinical Practice Research Database-Hospital Episode Statistics; Germany: IMS Disease Analyzer) covering the 2008-2012 period. RESULTS: Most eligible patients were treated with opioids for less than 6 months (UK: 78.7% and Germany: 93.7%) and indexed on weak opioids (UK: 89.5% and Germany: 88.6%). Most prescribed opioids were codeine (UK) and tramadol (Germany). Most prevalent comorbidities were dorsalgia/depression. Constipation was observed in 16.8%/17.4% (UK/Germany) of chronic users (>6 months). CONCLUSION: While both populations were highly morbid populations largely initiated on weak opioids, chronic use was less common in Germany.
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Keywords:
CPRD; drug utilization; electronic medical records; epidemiology; opioid; pain
Authors: Richard L Morrow; Colin R Dormuth; Michael Paterson; Muhammad M Mamdani; Tara Gomes; David N Juurlink Journal: BMJ Open Date: 2019-03-13 Impact factor: 2.692
Authors: Akira A Nair; Mihir A Velagapudi; Jonathan A Lang; Lakshmana Behara; Ravitheja Venigandla; Nishant Velagapudi; Christine T Fong; Mayumi Horibe; John D Lang; Bala G Nair Journal: PLoS One Date: 2020-07-31 Impact factor: 3.240
Authors: John Bedson; Ying Chen; Richard A Hayward; Julie Ashworth; Kate Walters; Kate M Dunn; Kelvin P Jordan Journal: Pain Date: 2016-07 Impact factor: 7.926