Literature DB >> 25299724

Mechanisms of dysfunction of the blood-brain barrier in critically ill patients: emphasis on the role of matrix metalloproteinases.

Hugo Rojas1, Cristiane Ritter1, Felipe Dal Pizzol1.   

Abstract

This paper aims to describe the physiological basis of the blood-brain barrier components and its properties. Additionally, the particular effects of metalloproteinases and their control over the extracellular matrix and its relationship with blood-brain barrier dysfunction are discussed. Finally, the role of metalloproteinases on changes in the central nervous system in critically ill patients is discussed.

Entities:  

Year:  2011        PMID： 25299724

Source DB:  PubMed          Journal:  Rev Bras Ter Intensiva        ISSN： 0103-507X


  6 in total

Review 1.  COVID-19's Clinical-Pathological Evidence in Relation to Its Repercussion on the Central and Peripheral Nervous System.

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Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

2.  Hierarchical Virtual Screening Based on Rocaglamide Derivatives to Discover New Potential Anti-Skin Cancer Agents.

Authors:  Igor V F Dos Santos; Rosivaldo S Borges; Guilherme M Silva; Lúcio R de Lima; Ruan S Bastos; Ryan S Ramos; Luciane B Silva; Carlos H T P da Silva; Cleydson B R Dos Santos
Journal:  Front Mol Biosci       Date:  2022-06-02

3.  Blockade of voltage-gated sodium channels inhibits invasion of endocrine-resistant breast cancer cells.

Authors:  Fatima H Mohammed; Maitham A Khajah; Ming Yang; William J Brackenbury; Yunus A Luqmani
Journal:  Int J Oncol       Date:  2015-11-09       Impact factor: 5.650

4.  Virtual Screening and Statistical Analysis in the Design of New Caffeine Analogues Molecules with Potential Epithelial Anticancer Activity.

Authors:  Josivan da Silva Costa; Karina da Silva Lopes Costa; Josiane Viana Cruz; Ryan da Silva Ramos; Luciane Barros Silva; Davi Do Socorro Barros Brasil; Carlos Henrique Tomich de Paula da Silva; Cleydson Breno Rodrigues Dos Santos; Williams Jorge da Cruz Macedo
Journal:  Curr Pharm Des       Date:  2018       Impact factor: 3.116

5.  Paracellular and Transcellular Leukocytes Diapedesis Are Divergent but Interconnected Evolutionary Events.

Authors:  Michel-Edwar Mickael; Norwin Kubick; Pavel Klimovich; Patrick Henckell Flournoy; Irmina Bieńkowska; Mariusz Sacharczuk
Journal:  Genes (Basel)       Date:  2021-02-10       Impact factor: 4.096

6.  Prognostic utility of early plasma matrix metalloproteinases -2 and -9 concentrations after severe traumatic brain injury.

Authors:  Rosane de Lima; Daniel Simon; Willy Deivson Leandro da Silva; Débora Dreher Nabinger; Andrea Regner
Journal:  Rev Bras Ter Intensiva       Date:  2020 Jul-Sep
  6 in total

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