Literature DB >> 2529893

A double-blind trial of treatment of seborrhoeic dermatitis with 2% ketoconazole cream compared with 1% hydrocortisone cream.

A Katsambas1, C Antoniou, E Frangouli, G Avgerinou, D Michailidis, J Stratigos.   

Abstract

Fifty patients with seborrhoeic dermatitis were treated with 2% ketoconazole cream (n = 24) or with 1% hydrocortisone cream (n = 26) for 4 weeks in a double-blind comparative study. These twice daily applications resulted in 87.2% symptomatic improvement for hydrocortisone vs. 81.6% for ketoconazole. The number of P. ovale yeasts was significantly reduced after the application of ketoconazole compared with hydrocortisone. The incidence of side-effects was low in both groups.

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Year:  1989        PMID: 2529893     DOI: 10.1111/j.1365-2133.1989.tb01429.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  8 in total

Review 1.  Topical corticosteroids. Which drug and when?

Authors:  B Giannotti; N Pimpinelli
Journal:  Drugs       Date:  1992-07       Impact factor: 9.546

Review 2.  Topical antifungals for seborrhoeic dermatitis.

Authors:  Enembe O Okokon; Jos H Verbeek; Jani H Ruotsalainen; Olumuyiwa A Ojo; Victor Nyange Bakhoya
Journal:  Cochrane Database Syst Rev       Date:  2015-05-02

Review 3.  An overview of topical antifungal therapy in dermatomycoses. A North American perspective.

Authors:  A K Gupta; T R Einarson; R C Summerbell; N H Shear
Journal:  Drugs       Date:  1998-05       Impact factor: 9.546

Review 4.  Immunology of diseases associated with Malassezia species.

Authors:  H Ruth Ashbee; E Glyn V Evans
Journal:  Clin Microbiol Rev       Date:  2002-01       Impact factor: 26.132

5.  Treatment of scalp and facial seborrheic dermatitis with desonide hydrogel 0.05%.

Authors:  Leon H Kircik
Journal:  J Clin Aesthet Dermatol       Date:  2009-02

6.  Optimizing treatment approaches in seborrheic dermatitis.

Authors:  Goldenberg Gary
Journal:  J Clin Aesthet Dermatol       Date:  2013-02

7.  In vitro modulation of keratinocyte-derived interleukin-1 alpha (IL-1 alpha) and peripheral blood mononuclear cell-derived IL-1 beta release in response to cutaneous commensal microorganisms.

Authors:  C E Walters; E Ingham; E A Eady; J H Cove; J N Kearney; W J Cunliffe
Journal:  Infect Immun       Date:  1995-04       Impact factor: 3.441

8.  Scalp Seborrheic Dermatitis and Dandruff Therapy Using a Herbal and Zinc Pyrithione-based Therapy of Shampoo and Scalp Lotion.

Authors:  Deganit Barak-Shinar; Lawrence J Green
Journal:  J Clin Aesthet Dermatol       Date:  2018-01-01
  8 in total

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