Literature DB >> 25297327

A highly sensitive europium nanoparticle-based immunoassay for detection of influenza A/B virus antigen in clinical specimens.

Panhe Zhang1, Sai Vikram Vemula2, Jiangqin Zhao1, Bingchen Du1, Haleyurgirisetty Mohan1, Jikun Liu1, Haja Sittana El Mubarak3, Marie L Landry4, Indira Hewlett2.   

Abstract

We report the development of a novel europium nanoparticle-based immunoassay (ENIA) for rapid detection of influenza A and influenza B viruses. The ENIA demonstrated sensitivities of 90.7% (147/162) for influenza A viruses and 81.80% (9/11) for influenza B viruses compared to those for an in-house reverse transcription (RT)-PCR assay in testing of influenza-positive clinical samples.
Copyright © 2014, American Society for Microbiology. All Rights Reserved.

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Year:  2014        PMID： 25297327      PMCID： PMC4313323          DOI： 10.1128/JCM.02635-14

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


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