Literature DB >> 25296078

Quality of life in patients with inflammatory bowel disease: importance of clinical, demographic and psychosocial factors.

Joana Magalhães1, Francisca Dias de Castro1, Pedro Boal Carvalho1, Maria João Moreira1, José Cotter1.   

Abstract

CONTEXT: Inflammatory bowel disease causes physical and psychosocial consequences that can affect the health related quality of life.
OBJECTIVES: To analyze the relationship between clinical and sociodemographic factors and quality of life in inflammatory bowel disease patients.
METHODS: Ninety two patients with Crohn's disease and 58 with ulcerative colitis, filled in the inflammatory bowel disease questionnaire (IBDQ-32) and a questionnaire to collect sociodemographic and clinical data. The association between categorical variables and IBDQ-32 scores was determined using Student t test. Factors statistically significant in the univariate analysis were included in a multivariate regression model.
RESULTS: IBDQ-32 scores were significantly lower in female patients (P<0.001), patients with an individual perception of a lower co-workers support (P<0.001) and career fulfillment (P<0.001), patients requiring psychological support (P = 0.010) and pharmacological treatment for anxiety or depression (P = 0.002). A multivariate regression analysis identified as predictors of impaired HRQOL the female gender (P<0.001) and the perception of a lower co-workers support (P = 0.025) and career fulfillment (P = 0.001).
CONCLUSIONS: The decrease in HRQQL was significantly related with female gender and personal perception of disease impact in success and social relations. These factors deserve a special attention, so timely measures can be implemented to improve the quality of life of patients.

Entities:  

Mesh:

Year:  2014        PMID: 25296078     DOI: 10.1590/s0004-28032014000300005

Source DB:  PubMed          Journal:  Arq Gastroenterol        ISSN: 0004-2803


  8 in total

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4.  Effects of vedolizumab on health-related quality of life in patients with ulcerative colitis: results from the randomised GEMINI 1 trial.

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6.  An Exploratory Study of Inflammatory Bowel Disease and the Psychosocial Factors Affecting Health-Related Quality of Life.

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7.  Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil.

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8.  Quality of life in inflammatory bowel disease patients: A cross-sectional study.

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  8 in total

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