Literature DB >> 25295461

Negative association between right bundle branch block and inducibility of ventricular tachyarrhythmias in Chagas disease.

Henrique Horta Veloso1.   

Abstract

Entities:  

Mesh:

Year:  2014        PMID: 25295461      PMCID: PMC4872959     

Source DB:  PubMed          Journal:  Einstein (Sao Paulo)        ISSN: 1679-4508


× No keyword cloud information.
I read with interest the article by Cedraz et al.( describing their findings on the electrophysiological study of 115 chagasic patients. The authors reported that the presence of right bundle branch block (RBBB) was associated with less induction of sustained ventricular tachycardia or ventricular fibrillation (VT/VF) in a univariate analysis. In 56 patients with RBBB, VT/VF was induced in 35 (37.5%), versus 21 of 59 cases (57.6%) without this disturbance (p=0.03). This difference resulted in an odds ratio of 0.44 (confidence interval 95%; 0.21-0.93). Unfortunately, the authors did not discuss this finding. Some studies have shown the inducibility of VT/VF as a predictor of mortality in Chagas disease.( The presence of RBBB was already demonstrated as an independent predictor of mortality in a multivariate analysis.( Therefore, the negative association between RBBB and inducibility of VT/VF in chagasic patients is a unique observation that should not be disregarded and needs further investigation. Li com interesse o estudo de Cedraz et al.,( que descreveram os achados do estudo eletrofisiológico de 115 chagásicos. Os autores demonstraram que a presença do bloqueio do ramo direito (BRD) esteve relacionada a menor indução de taquicardia ventricular sustentada ou fibrilação ventricular (TV/FV) pela análise univariada. Nos 56 pacientes com BRD, TV/FV foi induzida em 35 (37,5%) contra 21 de 59 casos (57,6%) sem essa alteração (p=0,03). Essa diferença resultou em uma odds ratio de 0,44 (intervalo de confiança de 95% de 0,21-0,93). Infelizmente, não houve discussão quanto a esse achado. Alguns estudos demonstraram a indutibilidade de TV/FV como preditor de mortalidade na cardiopatia chagásica.( Quanto ao BRD, sua presença já foi demonstrada como preditora independente de mortalidade em análise multivariada.( Portanto, a associação negativa entre BRD e indutibilidade de TV/FV em chagásicos é um achado original, que não deve ser desprezado, e suscita interesse para investigações mais aprofundadas.
  5 in total

1.  Predictive value of clinical and electrophysiological variables in patients with chronic chagasic cardiomyopathy and nonsustained ventricular tachycardia.

Authors:  R M Silva; M Z Távora; F A Gondim; N Metha; V M Hara; A A Paola
Journal:  Arq Bras Cardiol       Date:  2000-07       Impact factor: 2.000

Review 2.  Predictors of mortality in chronic Chagas disease: a systematic review of observational studies.

Authors:  Anis Rassi; Anis Rassi; Sérgio G Rassi
Journal:  Circulation       Date:  2007-03-06       Impact factor: 29.690

3.  Echocardiographic and Clinical Predictors of Mortality in Chronic Chagas' Disease.

Authors:  Luis A. Rodriguez-Salas; Eduardo Klein; Harry Acquatella; Franco Catalioti; Jose Ramon Gomez-Mancebo; Hector Gonzalez; Fernando Bosch; Juan Jose Puigbo
Journal:  Echocardiography       Date:  1998-04       Impact factor: 1.724

4.  Clinical usefulness of electrophysiologic testing in patients with ventricular tachycardia and chronic chagasic cardiomyopathy treated with amiodarone or sotalol.

Authors:  Luiz R Leite; Guilherme Fenelon; Aloyr Simoes; Georgia G Silva; Paul A Friedman; Angelo A V de Paola
Journal:  J Cardiovasc Electrophysiol       Date:  2003-06

5.  Electrophysiological characteristics of Chagas disease.

Authors:  Swellen Schuenemann Cedraz; Paulo Christo Coutinho da Silva; Ricardo Katsumi Yendo Minowa; Juliano Furtado de Aragão; Danilo Victor Silva; Carlos Morillo; Dalmo Antonio Ribeiro Moreira; Ricardo Garbe Habib; Bruno Pereira Valdigem; Luciana Vidal Armaganijan
Journal:  Einstein (Sao Paulo)       Date:  2013 Jul-Sep
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.