Literature DB >> 2529489

Altered glycosylation of surface glycoproteins in tumor cells and its clinical application.

A Kobata1.   

Abstract

Appearance of large Asn-linked sugar chains in the surface glycoprotein is one of the most widely found phenomena in malignant cells and is called the Warren-Glick phenomenon. Comparative study of the sugar chain structures of the surface glycoproteins of cultured cells and their malignant transformants revealed that the altered glycosylation is induced by enhancement of N-acetyl-glucosaminyltransferase V. The change seems to be highly correlated with the metastatic potential of tumor cells.

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Year:  1989        PMID： 2529489     DOI： 10.1111/j.1600-0749.1989.tb00209.x

Source DB:  PubMed          Journal:  Pigment Cell Res        ISSN： 0893-5785


  10 in total

1.  Glycosylation-site-selective synthesis of N-acetyl-lactosamine repeats in bis-glycosylated human lysozyme.

Authors:  R Melcher; A Hillebrand; U Bahr; B Schröder; M Karas; A Hasilik
Journal:  Biochem J       Date:  2000-06-15       Impact factor: 3.857

Review 2.  Mass spectrometry based glycoproteomics--from a proteomics perspective.

Authors:  Sheng Pan; Ru Chen; Ruedi Aebersold; Teresa A Brentnall
Journal:  Mol Cell Proteomics       Date:  2010-08-24       Impact factor: 5.911

3.  Enhanced expression of the β4-galactosyltransferase 2 gene impairs mammalian tumor growth.

Authors:  M Tagawa; K Shirane; L Yu; T Sato; S Furukawa; H Mizuguchi; R Kuji; K Kawamura; N Takahashi; K Kato; S Hayakawa; S Sawada; K Furukawa
Journal:  Cancer Gene Ther       Date:  2014-06-06       Impact factor: 5.987

4.  Label-free quantitative proteomics and N-glycoproteomics analysis of KRAS-activated human bronchial epithelial cells.

Authors:  Putty-Reddy Sudhir; Chein-Hung Chen; Madireddy Pavana Kumari; Mei-Jung Wang; Chih-Chiang Tsou; Ting-Yi Sung; Jeou-Yuan Chen; Chung-Hsuan Chen
Journal:  Mol Cell Proteomics       Date:  2012-07-03       Impact factor: 5.911

Review 5.  Sialidase and malignancy: a minireview.

Authors:  Taeko Miyagi; Tadashi Wada; Kazunori Yamaguchi; Keiko Hata
Journal:  Glycoconj J       Date:  2004       Impact factor: 2.916

6.  Increasing the productivity of glycopeptides analysis by using higher-energy collision dissociation-accurate mass-product-dependent electron transfer dissociation.

Authors:  Julian Saba; Sucharita Dutta; Eric Hemenway; Rosa Viner
Journal:  Int J Proteomics       Date:  2012-05-30

Review 7.  Glycoproteins and glycoproteomics in pancreatic cancer.

Authors:  Sheng Pan; Teresa A Brentnall; Ru Chen
Journal:  World J Gastroenterol       Date:  2016-11-14       Impact factor: 5.742

8.  Integrated glycoproteomics demonstrates fucosylated serum paraoxonase 1 alterations in small cell lung cancer.

Authors:  Jung-Mo Ahn; Hye-Jin Sung; Yeon-Hee Yoon; Byung-Gyu Kim; Won Suk Yang; Cheolju Lee; Hae-Min Park; Bum-Jin Kim; Byung-Gee Kim; Soo-Youn Lee; Hyun-Joo An; Je-Yoel Cho
Journal:  Mol Cell Proteomics       Date:  2013-10-01       Impact factor: 5.911

9.  Genomic alterations in mucins across cancers.

Authors:  Ryan J King; Fang Yu; Pankaj K Singh
Journal:  Oncotarget       Date:  2017-05-17

10.  Screening Method for Anti-Colon Cancer Drugs Using Two Sensor Cell Lines with Human β4-Galactosyltransferase 4 Gene Promoters.

Authors:  Naomichi Fukushima; Atena Sugiyama; Takeshi Sato
Journal:  Sensors (Basel)       Date:  2018-08-06       Impact factor: 3.576
  10 in total

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