Satomi Noguchi1, Satoshi Toyokawa2, Yuji Miyoshi3, Yasuo Suyama4, Kazuo Inoue5, Yasuki Kobayashi2. 1. Department of Public Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan Department of Health Policy and Technology Assessment, National Institute of Public Health, Saitama, Japan. 2. Department of Public Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. 3. Division of Health Promotion, Meiji Yasuda Life Insurance Company, Tokyo, Japan. 4. Meiji Yasuda Shinjuku Medical Center, Meiji Yasuda Life Foundation of Health and Welfare, Tokyo, Japan. 5. Department of Community Medicine, Chiba Medical Center, Teikyo University School of Medicine, Chiba, Japan.
Abstract
BACKGROUND: An association between chronic oral infections and coronary heart disease has been suggested. METHODS: The study participants were male employees aged 36-59 years. Data were extracted from the MY Health Up Study, comprising a baseline questionnaire survey and succeeding annual health examinations for financial firm workers in Japan. Using a self-administered questionnaire at baseline, participants' oral status was classified into three types of periodontal indicators: (i) periodontal score, (ii) periodontitis and (iii) tooth loss (<5 and ≥5 teeth). An incidence of myocardial infarction (MI) was determined by annual health examination records. RESULTS: Of the 4037 candidates for follow-up in the baseline year of 2004, 3081 males were eligible for the analysis, 17 of whom experienced MI in the subsequent 5 years. The periodontal score model was associated with an increase in developing MI [odds ratio (OR) = 2.11, 95% confidence interval (CI) = 1.29-3.44], after adjusting for other confounding variables. The periodontitis (OR = 2.26, 95% CI = 0.84-6.02) and tooth loss (OR = 1.97, 95% CI = 0.71-5.45) models showed similar trends, although the difference was not significant. CONCLUSIONS: Periodontal disease may be a mild but independent risk factor for MI among Japanese male workers.
BACKGROUND: An association between chronic oral infections and coronary heart disease has been suggested. METHODS: The study participants were male employees aged 36-59 years. Data were extracted from the MY Health Up Study, comprising a baseline questionnaire survey and succeeding annual health examinations for financial firm workers in Japan. Using a self-administered questionnaire at baseline, participants' oral status was classified into three types of periodontal indicators: (i) periodontal score, (ii) periodontitis and (iii) tooth loss (<5 and ≥5 teeth). An incidence of myocardial infarction (MI) was determined by annual health examination records. RESULTS: Of the 4037 candidates for follow-up in the baseline year of 2004, 3081 males were eligible for the analysis, 17 of whom experienced MI in the subsequent 5 years. The periodontal score model was associated with an increase in developing MI [odds ratio (OR) = 2.11, 95% confidence interval (CI) = 1.29-3.44], after adjusting for other confounding variables. The periodontitis (OR = 2.26, 95% CI = 0.84-6.02) and tooth loss (OR = 1.97, 95% CI = 0.71-5.45) models showed similar trends, although the difference was not significant. CONCLUSIONS:Periodontal disease may be a mild but independent risk factor for MI among Japanese male workers.
Authors: Richard H Singer; Mark Stoutenberg; Daniel J Feaster; Jianwen Cai; WayWay M Hlaing; Lisa R Metsch; Christian R Salazar; Shirley M Beaver; Tracy L Finlayson; Gregory Talavera; Marc D Gellman; Neil Schneiderman Journal: J Periodontol Date: 2018-07-20 Impact factor: 6.993