Literature DB >> 25292262

Generics in chronic myeloid leukemia: current arguments for and against and the established evidence.

Teoman Soysal1, Ahmet Emre Eskazan, Muhlis Cem Ar.   

Abstract

Tyrosine kinase inhibitors became the mainstay of management in patients with chronic myeloid leukemia. The substantially high treatment cost has unfortunately been a major issue. Recent market entry of the imatinib generics are expected to lower the price and increase the availability of the drug worldwide. However, concerns about their efficacy and safety seem to slacken the approval of the generics in many countries. In this editorial, we discuss the current evidence on imatinib generics based mainly on Turkish experience and other limited data available.

Entities:  

Keywords:  chronic myeloid leukemia; generic; imatinib; tyrosine kinase inhibitor

Mesh:

Substances:

Year:  2014        PMID: 25292262     DOI: 10.1586/17474086.2014.966679

Source DB:  PubMed          Journal:  Expert Rev Hematol        ISSN: 1747-4094            Impact factor:   2.929


  3 in total

1.  The tolerability issue of generic imatinib in patients with chronic myeloid leukemia (Comment on Adi J. Klil-Drori et al., Haematologica 2019;104(7):e293).

Authors:  Ahmet Emre Eskazan; Teoman Soysal
Journal:  Haematologica       Date:  2019-07       Impact factor: 9.941

2.  Evolving treatment strategies in CML - moving from early and deep molecular responses to TKI discontinuation and treatment-free remission: is there a need for longer-term trial outcomes?

Authors:  Ahmet Emre Eşkazan
Journal:  Br J Clin Pharmacol       Date:  2018-06-03       Impact factor: 4.335

Review 3.  Radotinib and its clinical potential in chronic-phase chronic myeloid leukemia patients: an update.

Authors:  Ahmet Emre Eskazan; Dilek Keskin
Journal:  Ther Adv Hematol       Date:  2017-07-25
  3 in total

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