Literature DB >> 25291532

Does T-cell restriction to Ia limit the need for self-tolerance?

C Cowing1.   

Abstract

Why did two classes ofMHC molecule evolve as restricting elements in T-cell function? Here Carol Cowing discusses the hypothesis that incomplete self-tolerance may explain the necessity for class II MHC restriction.
Copyright © 1985. Published by Elsevier B.V.

Year:  1985        PMID： 25291532     DOI： 10.1016/0167-5699(85)90018-0

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  4 in total

Review 1.  I-E transgenic mice: a model system to dissect the regulation and function of MHC class II genes in vivo.

Authors:  L C Burkly; D Lo; R L Brinster; R A Flavell
Journal:  Immunol Res       Date:  1990       Impact factor: 2.829

2.  Tissue-specific expression of the HLA-DRA gene in transgenic mice.

Authors:  P Giacomini; A Ciucci; M R Nicotra; C Nastruzzi; G Feriotto; E Appella; R Gambari; L Pozzi; P G Natali
Journal:  Immunogenetics       Date:  1991       Impact factor: 2.846

Review 3.  HLA, immune response and disease.

Authors:  N K Mehra; V Taneja
Journal:  Indian J Pediatr       Date:  1989 Mar-Apr       Impact factor: 1.967

4.  Differential expression and regulation of major histocompatibility complex (MHC) products in neural and glial cells of the human fetal brain.

Authors:  T Mauerhoff; R Pujol-Borrell; R Mirakian; G F Bottazzo
Journal:  J Neuroimmunol       Date:  1988-07       Impact factor: 3.478
  4 in total

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