Literature DB >> 25290054

'Background' immunoglobulin production: measurement, biological significance and regulation.

R Benner1, A van Oudenaren1, M Björklund1, F Ivars1, D Holmberg1.   

Abstract

Every individual produces immunoglobulins, even under germfree conditions. This article discusses the measurement, biological significance and regulation of this 'spontaneous' ('background') immunoglobulin production. The authors relate this phenomenon to the original suggestions of Niels Kaj Jerne, in 1955, about the role of 'natural' circulating antibodies in antibody formation and the completeness of the repertoire of antigen-binding specificities as represented among the natural antibodies.
Copyright © 1982. Published by Elsevier B.V.

Year:  1982        PMID： 25290054     DOI： 10.1016/0167-5699(82)90010-X

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  4 in total

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Authors:  Victor Apanius; Ian C T Nisbet
Journal:  Oecologia       Date:  2005-09-27       Impact factor: 3.225

2.  Modulated red blood cell survival by membrane protein clustering.

Authors:  L Chiarantini; L Rossi; A Fraternale; M Magnani
Journal:  Mol Cell Biochem       Date:  1995-03-09       Impact factor: 3.396

3.  Basal immunoglobulin serum concentration and isotype distribution in relation to the polygenic control of antibody responsiveness in mice.

Authors:  O A Sant'Anna; D Mouton; O M Ibanez; Y Bouthillier; J C Mevel; M H Reis; G Biozzi
Journal:  Immunogenetics       Date:  1985       Impact factor: 2.846

4.  Lymphocyte function in human bone marrow. II. Characterization of an interleukin 2-sensitive T precursor-cell population.

Authors:  H M Dosch; C J Ledgley; D White; P Lam; G B Mills
Journal:  J Clin Immunol       Date:  1985-09       Impact factor: 8.317
  4 in total

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