Literature DB >> 25289500

Immune interferon: a pleiotropic lymphokine with multiple effects.

G Trinchieri1, B Perussia.   

Abstract

Immune (gamma) interferon (IFN-γ) is produced during an immune response by antigen-specific T cells and probably also by natural killer (NK) cells recruited by the T cell-product interleukin 2 (IL-2). IFN-γ was discovered and originally measured on the basis of its anti-viral activity, but its complex anti-cellular activities probably reflect its biological role more clearly. In this review, Giorgio Trinchieri and Bice Perussia discuss some aspects of the biology of IFN-γ, its pleiomorphic anti-cellular effects and its ability to modulate cellular responses to other regulatory factors.
Copyright © 1985. Published by Elsevier B.V.

Entities:  

Year:  1985        PMID： 25289500     DOI： 10.1016/0167-5699(85)90080-5

Source DB:  PubMed          Journal:  Immunol Today        ISSN： 0167-5699


  54 in total

1.  Modulation of transporter associated with antigen processing (TAP)-mediated peptide import into the endoplasmic reticulum by flavivirus infection.

Authors:  F Momburg; A Müllbacher; M Lobigs
Journal:  J Virol       Date:  2001-06       Impact factor: 5.103

Review 2.  Interferons 1992. How much of the promise has been realised?

Authors:  M A Volz; C H Kirkpatrick
Journal:  Drugs       Date:  1992-03       Impact factor: 9.546

3.  Ability of recombinant interferon gamma in vitro to restore the defective polymorphonuclear-cell- but not lymphocyte-mediated cytotoxic activities in patients with myelodysplastic syndromes.

Authors:  G De Sanctis; V Bottari; A Frezzolini; M Ficcardi; G De Rossi; M C Petti; F Mandelli; L Fontana
Journal:  Cancer Immunol Immunother       Date:  1992       Impact factor: 6.968

4.  Increased yield of high purity recombinant human interferon-gamma utilizing reversed phase column chromatography.

Authors:  Praveen K Reddy; Srinivasa G Reddy; Venkata R Narala; Sangita S Majee; Sudhakar Konda; Sripad Gunwar; Raju C Reddy
Journal:  Protein Expr Purif       Date:  2006-09-06       Impact factor: 1.650

5.  T-lymphocyte immuno-interferon binding in parkinsonian patients.

Authors:  P Bongioanni; C Mondino; M Borgna; B Boccardi; R Sposito; M Castagna
Journal:  J Neural Transm (Vienna)       Date:  1997       Impact factor: 3.575

Review 6.  Inflammatory and immune pathways in the pathogenesis of periodontal disease.

Authors:  Ali Cekici; Alpdogan Kantarci; Hatice Hasturk; Thomas E Van Dyke
Journal:  Periodontol 2000       Date:  2014-02       Impact factor: 7.589

7.  Induction of urinary interleukin-1 (IL-1), IL-2, IL-6, and tumour necrosis factor during intravesical immunotherapy with bacillus Calmette-Guérin in superficial bladder cancer.

Authors:  E C De Boer; W H De Jong; P A Steerenberg; L A Aarden; E Tetteroo; E R De Groot; A P Van der Meijden; P D Vegt; F M Debruyne; E J Ruitenberg
Journal:  Cancer Immunol Immunother       Date:  1992       Impact factor: 6.968

8.  Interferon-gamma and tumour necrosis factor production in patients with Helicobacter pylori infection.

Authors:  X J Fan; A Chua; M A O'Connell; D Kelleher; P W Keeling
Journal:  Ir J Med Sci       Date:  1993-10       Impact factor: 1.568

Review 9.  Mechanisms of action of bacillus Calmette-Guérin in the treatment of superficial bladder cancer.

Authors:  J J Patard; D K Chopin; L Boccon-Gibod
Journal:  World J Urol       Date:  1993       Impact factor: 4.226

Review 10.  Oligodendroglial response to the immune cytokine interferon gamma.

Authors:  B Popko; K D Baerwald
Journal:  Neurochem Res       Date:  1999-02       Impact factor: 3.996
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