Murray Baron1, Marie Hudson1, Solène Tatibouet2, Russell Steele1, Ernest Lo2, Sabrina Gravel2, Geneviève Gyger1, Tarek El Sayegh2, Janet Pope2, Audrey Fontaine2, Ariel Masetto2, Debora Matthews2, Evelyn Sutton2, Norman Thie2, Niall Jones2, Maria Copete2, Dean Kolbinson2, Janet Markland2, Getulio Nogueira-Filho2, David Robinson2, Mervyn Gornitsky2. 1. Division of Rheumatology, Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, McGill University, Montreal, QC, Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital, Montreal, Department of Mathematics and Statistics, Dentistry, Division of Rheumatology, Department of Medicine, University of Western Ontario, London, ON, Dentistry, Clinique Dentaire Ayotte et associées, Department of Rheumatology, Université de Sherbrooke, Sherbrooke, Division of Periodontics and Oro-facial Pain, Faculty of Dentistry, Dalhousie University, Division of Rheumatology, Faculty of Medicine, Dalhousie University, Halifax, TMD/Orofacial Pain Graduate Program, School of Dentistry, Department of Medicine, University of Alberta, Edmonton, AB, College of Dentistry, Division of Rheumatology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Department of Periodontology, Faculty of Dentistry, Rheumatology, Faculty of Medicine, University of Manitoba, Winnipeg, MB and Department of Dentistry, SMBD Jewish General Hospital, McGill University, Montreal, QC, Canada. Division of Rheumatology, Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, McGill University, Montreal, QC, Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital, Montreal, Department of Mathematics and Statistics, Dentistry, Division of Rheumatology, Department of Medicine, University of Western Ontario, London, ON, Dentistry, Clinique Dentaire Ayotte et associées, Department of Rheumatology, Université de Sherbrooke, Sherbrooke, Division of Periodontics and Oro-facial Pain, Faculty of Dentistry, Dalhousie University, Division of Rheumatology, Faculty of Medicine, Dalhousie University, Halifax, TMD/Orofacial Pain Graduate Program, School of Dentistry, Department of Medicine, University of Alberta, Edmonton, AB, College of Dentistry, Division of Rheumatology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Department of Period 2. Division of Rheumatology, Department of Internal Medicine, Division of Rheumatology, Faculty of Medicine, McGill University, Montreal, QC, Epidemiology, Lady Davis Institute, SMBD Jewish General Hospital, Montreal, Department of Mathematics and Statistics, Dentistry, Division of Rheumatology, Department of Medicine, University of Western Ontario, London, ON, Dentistry, Clinique Dentaire Ayotte et associées, Department of Rheumatology, Université de Sherbrooke, Sherbrooke, Division of Periodontics and Oro-facial Pain, Faculty of Dentistry, Dalhousie University, Division of Rheumatology, Faculty of Medicine, Dalhousie University, Halifax, TMD/Orofacial Pain Graduate Program, School of Dentistry, Department of Medicine, University of Alberta, Edmonton, AB, College of Dentistry, Division of Rheumatology, College of Medicine, University of Saskatchewan, Saskatoon, SK, Department of Periodontology, Faculty of Dentistry, Rheumatology, Faculty of Medicine, University of Manitoba, Winnipeg, MB and Department of Dentistry, SMBD Jewish General Hospital, McGill University, Montreal, QC, Canada.
Abstract
OBJECTIVE: Both oral and global health-related quality of life (HRQoL) are markedly impaired in SSc. In this study we aimed to determine the degree of association between oral HRQoL and global HRQoL in SSc. METHODS: Subjects were recruited from the Canadian Scleroderma Research Group registry. Global HRQoL was measured using the Medical Outcomes Trust 36-item Short Form Health Survey (SF-36) and oral HRQoL with the Oral Health Impact Profile (OHIP). The Medsger Disease Severity Score was used to determine organ involvement. Multivariate regression models determined the independent association of the OHIP with the SF-36 after adjusting for confounders. RESULTS: This study included 156 SSc subjects. The majority (90%) were women, with a mean age of 56 years, mean disease duration 13.8 years (s.d. 8.5) and 29% of the subjects had dcSSc. Mean total OHIP score was 40.8 (s.d. 32.4). Mean SF-36 mental component summary (MCS) score was 49.7 (s.d. 11.1) and physical component summary (PCS) score was 37.0 (s.d. 10.7). In adjusted analyses, the total OHIP score was significantly associated with the SF-36 MCS and PCS, accounting for 9.7% and 5.6% of their respective variances. Measures of disease severity were not related to OHIP score. CONCLUSION: Oral HRQoL in SSc is independently associated with global HRQoL. Oral HRQoL, however, is not related to physician-assessed disease severity. This suggests that physicians may be disregarding issues related to oral health. HRQoL is an additional dimension of HRQoL not captured by generic instruments such as the SF-36.
OBJECTIVE: Both oral and global health-related quality of life (HRQoL) are markedly impaired in SSc. In this study we aimed to determine the degree of association between oral HRQoL and global HRQoL in SSc. METHODS: Subjects were recruited from the Canadian Scleroderma Research Group registry. Global HRQoL was measured using the Medical Outcomes Trust 36-item Short Form Health Survey (SF-36) and oral HRQoL with the Oral Health Impact Profile (OHIP). The Medsger Disease Severity Score was used to determine organ involvement. Multivariate regression models determined the independent association of the OHIP with the SF-36 after adjusting for confounders. RESULTS: This study included 156 SSc subjects. The majority (90%) were women, with a mean age of 56 years, mean disease duration 13.8 years (s.d. 8.5) and 29% of the subjects had dcSSc. Mean total OHIP score was 40.8 (s.d. 32.4). Mean SF-36 mental component summary (MCS) score was 49.7 (s.d. 11.1) and physical component summary (PCS) score was 37.0 (s.d. 10.7). In adjusted analyses, the total OHIP score was significantly associated with the SF-36 MCS and PCS, accounting for 9.7% and 5.6% of their respective variances. Measures of disease severity were not related to OHIP score. CONCLUSION: Oral HRQoL in SSc is independently associated with global HRQoL. Oral HRQoL, however, is not related to physician-assessed disease severity. This suggests that physicians may be disregarding issues related to oral health. HRQoL is an additional dimension of HRQoL not captured by generic instruments such as the SF-36.
Authors: E C LeRoy; C Black; R Fleischmajer; S Jablonska; T Krieg; T A Medsger; N Rowell; F Wollheim Journal: J Rheumatol Date: 1988-02 Impact factor: 4.666
Authors: Judith A Jones; Nancy R Kressin; Lewis E Kazis; Donald R Miller; Avron Spiro; Austin Lee; Raul I Garcia Journal: J Ambul Care Manage Date: 2006 Apr-Jun
Authors: Dinesh Khanna; Daniel E Furst; Philip J Clements; Grace S Park; Ron D Hays; Jeonglim Yoon; Joseph H Korn; Peter A Merkel; Naomi Rothfield; Fredrick M Wigley; Larry W Moreland; Richard Silver; Virginia D Steen; Michael Weisman; Maureen D Mayes; David H Collier; Thomas A Medsger; James R Seibold Journal: J Rheumatol Date: 2005-05 Impact factor: 4.666
Authors: S Maddali Bongi; A Del Rosso; I Miniati; F Galluccio; G Landi; G Tai; M Matucci-Cerinic Journal: Rheumatol Int Date: 2011-08-17 Impact factor: 2.631
Authors: P Clements; P Lachenbruch; J Siebold; B White; S Weiner; R Martin; A Weinstein; M Weisman; M Mayes; D Collier Journal: J Rheumatol Date: 1995-07 Impact factor: 4.666
Authors: Daniel N Reed; David L Hall; James H Cottle; Katherine Frimenko; Christina K Horton; Farah Abu Sharkh; Rachel Beckett; Brandon Hernandez; Hannah Mabe; Shadee T Mansour; Sebastian A Rodriguez; Bradley Weprin; Leigh E Yarborough Journal: Clin Case Rep Date: 2020-01-17