RATIONALE: Current research suggests that glucose facilitates performance on cognitive tasks which possess an episodic memory component and a relatively high level of cognitive demand. However, the extent to which this glucose facilitation effect is uniform across the lifespan is uncertain. METHODS: This study was a repeated measures, randomised, placebo-controlled, cross-over trial designed to assess the cognitive effects of glucose in younger and older adults under single and dual task conditions. Participants were 24 healthy younger (average age 20.6 years) and 24 healthy older adults (average age 72.5 years). They completed a recognition memory task after consuming drinks containing 25 g glucose and a placebo drink, both in the presence and absence of a secondary tracking task. RESULTS AND CONCLUSIONS: Glucose enhanced recognition memory response time and tracking precision during the secondary task, in older adults only. These findings do not support preferential targeting of hippocampal function by glucose, rather they suggest that glucose administration differentially increases the availability of attentional resources in older individuals.
RATIONALE: Current research suggests that glucose facilitates performance on cognitive tasks which possess an episodic memory component and a relatively high level of cognitive demand. However, the extent to which this glucose facilitation effect is uniform across the lifespan is uncertain. METHODS: This study was a repeated measures, randomised, placebo-controlled, cross-over trial designed to assess the cognitive effects of glucose in younger and older adults under single and dual task conditions. Participants were 24 healthy younger (average age 20.6 years) and 24 healthy older adults (average age 72.5 years). They completed a recognition memory task after consuming drinks containing 25 g glucose and a placebo drink, both in the presence and absence of a secondary tracking task. RESULTS AND CONCLUSIONS: Glucose enhanced recognition memory response time and tracking precision during the secondary task, in older adults only. These findings do not support preferential targeting of hippocampal function by glucose, rather they suggest that glucose administration differentially increases the availability of attentional resources in older individuals.
Authors: Sandra I Sünram-Lea; Jonathan K Foster; Paula Durlach; Catalina Perez Journal: Psychopharmacology (Berl) Date: 2002-02-08 Impact factor: 4.530
Authors: Andrew Scholey; Helen Macpherson; Sandra Sünram-Lea; Jade Elliott; Con Stough; David Kennedy Journal: Neuropharmacology Date: 2012-07-02 Impact factor: 5.250
Authors: Josep Bassaganya-Riera; Elliot M Berry; Ellen E Blaak; Barbara Burlingame; Johannes le Coutre; Willem van Eden; Ahmed El-Sohemy; J Bruce German; Dietrich Knorr; Christophe Lacroix; Maurizio Muscaritoli; David C Nieman; Michael Rychlik; Andrew Scholey; Mauro Serafini Journal: Front Nutr Date: 2021-02-09