Literature DB >> 25288228

The role of integrin antagonists in the treatment of inflammatory bowel disease.

Poonam Beniwal-Patel1, Sumona Saha.   

Abstract

INTRODUCTION: Ulcerative colitis (UC) and Crohn's disease are chronic inflammatory diseases of the bowel associated with complex inflammatory cascades within the mucosal lining of the gut. AREAS COVERED: INTEGRINS and their use as therapies in UC and Crohn's. EXPERT OPINION: The anti-adhesion molecules are a welcome addition to the armamentarium of medical therapies for inflammatory bowel disease.

Entities:  

Keywords:  Crohn’s disease; immunomodulator; inflammation; integrin; natalizumab; ulcerative colitis; vedolizumab

Mesh:

Substances:

Year:  2014        PMID: 25288228     DOI: 10.1517/14712598.2014.967209

Source DB:  PubMed          Journal:  Expert Opin Biol Ther        ISSN: 1471-2598            Impact factor:   4.388


  3 in total

Review 1.  New and emerging therapies for acute and chronic graft versus host disease.

Authors:  LaQuisa Hill; Amin Alousi; Partow Kebriaei; Rohtesh Mehta; Katayoun Rezvani; Elizabeth Shpall
Journal:  Ther Adv Hematol       Date:  2017-11-28

2.  Anti-inflammatory effects of Fagopyrum cymosum administered as a potential drug for ulcerative colitis.

Authors:  Fei Ge; Shilin Zhu; Lina Liu; Jing Yan; Yu Ji; Zhiguang Sun
Journal:  Exp Ther Med       Date:  2017-09-20       Impact factor: 2.447

3.  Combination Therapy of PEG-HM-3 and Methotrexate Retards Adjuvant-Induced Arthritis.

Authors:  Jingchao Hao; Xiaodong Wu; Sarra Setrerrahmane; Kun Qian; Yueying Hou; Liting Yu; Chenyu Lin; Qianqian Wu; Hanmei Xu
Journal:  Int J Mol Sci       Date:  2017-07-21       Impact factor: 5.923

  3 in total

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