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Literature DB >> 25287688

Molecular-genetic imaging of cancer.

Il Minn¹, Mitchell E Menezes², Siddik Sarkar², Keerthi Yarlagadda¹, Swadesh K Das³, Luni Emdad⁴, Devanand Sarkar⁴, Paul B Fisher⁴, Martin G Pomper⁵.

Abstract

Molecular-genetic imaging of cancer using nonviral delivery systems has great potential for clinical application as a safe, efficient, noninvasive tool for visualization of various cellular processes including detection of cancer, and its attendant metastases. In recent years, significant effort has been expended in overcoming technical hurdles to enable clinical adoption of molecular-genetic imaging. This chapter will provide an introduction to the components of molecular-genetic imaging and recent advances on each component leading to safe, efficient clinical applications for detecting cancer. Combination with therapy, namely, generating molecular-genetic theranostic constructs, will provide further impetus for clinical translation of this promising technology.

Entities: CellLine Chemical Disease Gene Mutation Species

Keywords: Bioluminescence; Metastasis; Molecular imaging; PET; Promoter

Mesh：

Year: 2014 PMID： 25287688 PMCID： PMC4339000 DOI： 10.1016/B978-0-12-411638-2.00004-5

Source DB: PubMed Journal: Adv Cancer Res ISSN： 0065-230X Impact factor: 6.242

157 in total

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11 in total

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Journal: Cancer Res Date: 2019-09-17 Impact factor: 12.701

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