Literature DB >> 25287582

Pleomorphic adenomas: post-operative radiotherapy is unnecessary following primary incomplete excision: a retrospective review.

B F Robertson1, G A Robertson2, T Shoaib2, D S Soutar2, S Morley2, A G Robertson3.   

Abstract

BACKGROUND: Current standard treatment of Pleomorphic Salivary Adenoma (PSA) of the Parotid Gland is by surgical excision. The management of incomplete excision remains undecided with post-operative radiotherapy advocated by some and observation by others.
METHODS: 190 patients who underwent resection of PSA of the parotid gland within the West of Scotland region from 1981 to 2008 were identified and data collected.
RESULTS: 78/190 patients had a primary incomplete excision. 25/78 received post-operative radiotherapy and 53 were observed. Recurrences occurred in 11/53 in those observed and in 1/25 of those who received radiotherapy. 21/25 complained of significant side effects from the radiotherapy. 38 surgeons performed 190 procedures, with a range of experience from 1 to28 procedures.
CONCLUSIONS: Radiotherapy does appear to reduce recurrence with incomplete excision, however it is associated with significant side effects. We therefore feel radiotherapy should not be routinely recommended. Subspecialisation should be adopted to increase the operating surgeon's experience.
Copyright © 2014 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Incomplete excision; Pleomorphic Adenomas; Radiotherapy; Recurrence

Mesh:

Year:  2014        PMID: 25287582     DOI: 10.1016/j.bjps.2014.09.030

Source DB:  PubMed          Journal:  J Plast Reconstr Aesthet Surg        ISSN: 1748-6815            Impact factor:   2.740


  4 in total

1.  Clinicopathologic Characteristics and Prognostic Factors of Primary and Recurrent Pleomorphic Adenoma: A Single Institution Retrospective Study of 705 Cases.

Authors:  Bayan Alzumaili; Bin Xu; Maelle Saliba; Abderhman Abuhashem; Ian Ganly; Ronald Ghossein; Nora Katabi
Journal:  Am J Surg Pathol       Date:  2021-11-15       Impact factor: 6.298

Review 2.  Why Do Parotid Pleomorphic Adenomas Recur? A Systematic Review of Pathological and Surgical Variables.

Authors:  Pavel Dulguerov; Jelena Todic; Marc Pusztaszeri; Naif H Alotaibi
Journal:  Front Surg       Date:  2017-05-15

3.  Radiation Therapy After Surgical Resection Improves Outcomes for Patients With Recurrent Pleomorphic Adenoma.

Authors:  Sarah E Nicholas; Wei Fu; Angela L Liang; Regina DeLuna; Luka Vujaskovic; Justin Bishop; Brandi R Page; Harry Quon; Christine Gourin; Carole Fakhry; David Eisele; Ana P Kiess
Journal:  Adv Radiat Oncol       Date:  2021-03-02

4.  Contemporary Management of Benign and Malignant Parotid Tumors.

Authors:  Jovanna Thielker; Maria Grosheva; Stephan Ihrler; Andrea Wittig; Orlando Guntinas-Lichius
Journal:  Front Surg       Date:  2018-05-11
  4 in total

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