Literature DB >> 25287386

Genuair(®) in chronic obstructive pulmonary disease: a novel, user-friendly, multidose, dry-powder inhaler.

Job van der Palen1.   

Abstract

Inhaled corticosteroids and bronchodilators, which are pivotal to the management of respiratory diseases, are delivered by numerous devices, including pressurized metered-dose inhalers and dry-powder inhalers. However, patient adherence to these medications is suboptimal and incorrect inhaler technique is endemic, meaning that insufficient drug quantities are frequently delivered to the lungs. Genuair(®) (Almirall SA, Spain) is a novel, breath-actuated, multidose dry-powder inhaler designed to achieve reliable and effective delivery of inhaled medicines - including aclidinium bromide - to patients with chronic obstructive pulmonary disease. In addition to describing Genuair's design, which incorporates multiple feedback mechanisms in order to confirm effective medication uptake, this article discusses the performance characteristics of the inhaler, its efficiency in terms of drug deposition and the results of recent patient preference and satisfaction studies.

Entities:  

Mesh:

Year:  2014        PMID: 25287386     DOI: 10.4155/tde.14.49

Source DB:  PubMed          Journal:  Ther Deliv        ISSN: 2041-5990


  3 in total

1.  Acceptability and preference of three inhalation devices assessed by the Handling Questionnaire in asthma and COPD patients.

Authors:  Roberto W Dal Negro; Massimiliano Povero
Journal:  Multidiscip Respir Med       Date:  2016-02-10

2.  Dry-powder inhalers in patients with persistent airflow limitation: usability and preference.

Authors:  Roberto W Dal Negro; Massimiliano Povero
Journal:  Multidiscip Respir Med       Date:  2016-09-05

Review 3.  Inhaler Devices for Delivery of LABA/LAMA Fixed-Dose Combinations in Patients with COPD.

Authors:  Anthony D'Urzo; Kenneth R Chapman; James F Donohue; Peter Kardos; M Reza Maleki-Yazdi; David Price
Journal:  Pulm Ther       Date:  2019-03-13
  3 in total

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