Literature DB >> 25287240

Bowel ischaemia and cocaine consumption; case study and review of the literature.

Almudena Martínez-Vieira, Alonso Camacho-Ramírez, Antonio Díaz-Godoy, Antonio Calvo-Durán, Carmen María Pérez-Alberca, Coral de-la-Vega-Olías, Gloria Muñoz-Arias, Manuel Balbuena-García, Assad Najeb, Vicente Vega-Ruiz.   

Abstract

BACKGROUND: Amongst others, cocaine consumption has a detrimental effect in the vascular supply to the mesenteric area causing abdominal ischemic changes. Early recognition of these changes and adequate treatment are essential to avoid serious complications and possible death of the patient from sepsis. CASE REPORT: In this case study, the subject is a 40-years-old gentleman presenting with acute abdominal pain due to multiple ischemic changes in both small bowel and sigmoid loops. The patient required emergency surgical intervention consisting of bowel resection and anastomosis. The pathologic analysis of the segment showed transmural necrosis and necrotizing phlebitis caused by the ingestion of drugs or toxic agents. The patient later confirmed the habitual consumption of cocaine. DISCUSSION: The increase in cocaine consumption and other recreational toxins substructed from erythroyilon coca alkaloids amongst young people have generated a large number of admissions to Hospital Accident and Emergency Departments with patients complaining of acute abdominal pain. In many of these cases, surgical intervention is required and in some cases patients will sadly die without a proper diagnosis. Some of the most common effects of cocaine and its compounds includes; hollow viscus perforation, gastro-intestinal bleed, and other vascular problems such as enteritis and ischemic colitis. It appears clear that there is a great need for an advance history taking of these patients and their habit to cocaine and other drugs together with a urine test for drug screening. These together with a suspicion of a non- occlusive ischemic bowel caused by the effects of cocaine in young adults with no cardiac risk factors will guide clinicians and establish, and plan the correct treatment for these categories of patients.

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Year:  2014        PMID: 25287240

Source DB:  PubMed          Journal:  Rev Esp Enferm Dig        ISSN: 1130-0108            Impact factor:   2.086


  6 in total

1.  Emerging and Underrecognized Complications of Illicit Drug Use.

Authors:  Alysse G Wurcel; Elisabeth A Merchant; Roger P Clark; David R Stone
Journal:  Clin Infect Dis       Date:  2015-08-12       Impact factor: 9.079

2.  Gastric perforation secondary to ingestion of a plastic bag.

Authors:  Y M Goh; I M Shapey; K Riyad
Journal:  Ann R Coll Surg Engl       Date:  2016-01-07       Impact factor: 1.891

Review 3.  Small Bowel Lesions Mimicking Crohn's Disease.

Authors:  David B Sachar
Journal:  Curr Gastroenterol Rep       Date:  2018-08-06

4.  A Retrospective Analysis of Nonocclusive Mesenteric Ischemia in Medical and Surgical ICU Patients: Clinical Data on Demography, Clinical Signs, and Survival.

Authors:  Klaus Stahl; Markus Busch; Sabine K Maschke; Andrea Schneider; Michael P Manns; Jan Fuge; Olaf Wiesner; Bernhard C Meyer; Marius M Hoeper; Jan B Hinrichs; Sascha David
Journal:  J Intensive Care Med       Date:  2019-03-25       Impact factor: 3.510

5.  Methamphetamine consumption and life-threatening abdominal complications: A case report.

Authors:  Xiaojing Zou; Haiyan Huang; Le Yang; Hong Liu; Yongfeng Li; Qin Xia; Shiying Yuan; Shanglong Yao
Journal:  Medicine (Baltimore)       Date:  2018-05       Impact factor: 1.889

6.  Chemical Colitis Induced by Low-dose Hydrogen Peroxide Enema in a Cocaine User.

Authors:  Jason Galo; Michelle Zaydlin; Diego A Celli-Cabada
Journal:  Cureus       Date:  2020-02-17
  6 in total

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