Literature DB >> 2528689

Transforming mutant v-mos protein kinases that are deficient in in vitro autophosphorylation.

R S Freeman1, D J Donoghue.   

Abstract

We investigated the importance of specific serine residues for autophosphorylation and transformation by serine-threonine protein kinase p37mos. When either serine 326 or 358 was replaced with alanine, the resulting mutant protein retained the ability to transform NIH 3T3 cells but failed to autophosphorylate in vitro. These studies represent the first functional uncoupling of these two activities for p37mos.

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Year:  1989        PMID： 2528689      PMCID： PMC362478          DOI： 10.1128/mcb.9.9.4087-4090.1989

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  18 in total

1.  Use of site-specific antipeptide antibodies to perturb the serine kinase catalytic activity of p37mos.

Authors:  S A Maxwell; R B Arlinghaus
Journal:  J Virol       Date:  1985-09       Impact factor: 5.103

Review 2.  The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.

Authors:  S K Hanks; A M Quinn; T Hunter
Journal:  Science       Date:  1988-07-01       Impact factor: 47.728

3.  A virus-induced rhabdomyosarcoma of mice.

Authors:  J B Moloney
Journal:  Natl Cancer Inst Monogr       Date:  1966-09

4.  Rapid and efficient site-specific mutagenesis without phenotypic selection.

Authors:  T A Kunkel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

5.  Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors.

Authors:  M J Zoller; M Smith
Journal:  Methods Enzymol       Date:  1983       Impact factor: 1.600

6.  Expression of a recombinant DNA gene coding for the vesicular stomatitis virus nucleocapsid protein.

Authors:  J Sprague; J H Condra; H Arnheiter; R A Lazzarini
Journal:  J Virol       Date:  1983-02       Impact factor: 5.103

7.  Recognition of mos-related proteins with an antiserum to a peptide of the v-mos gene product.

Authors:  G E Gallick; J T Sparrow; B Singh; S A Maxwell; L H Stanker; R B Arlinghaus
Journal:  J Gen Virol       Date:  1985-05       Impact factor: 3.891

8.  A defined subgenomic fragment of in vitro synthesized Moloney sarcoma virus DNA can induce cell transformation upon transfection.

Authors:  P Andersson; M P Goldfarb; R A Weinberg
Journal:  Cell       Date:  1979-01       Impact factor: 41.582

9.  Nucleotide sequence and biochemical activities of the Moloney murine sarcoma virus strain HT-1 mos gene.

Authors:  A Seth; G F Vande Woude
Journal:  J Virol       Date:  1985-10       Impact factor: 5.103

10.  Amino acid sequence of the catalytic subunit of bovine type II adenosine cyclic 3',5'-phosphate dependent protein kinase.

Authors:  S Shoji; L H Ericsson; K A Walsh; E H Fischer; K Titani
Journal:  Biochemistry       Date:  1983-07-19       Impact factor: 3.162
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  5 in total

1.  mos gene transforming efficiencies correlate with oocyte maturation and cytostatic factor activities.

Authors:  N Yew; M Oskarsson; I Daar; D G Blair; G F Vande Woude
Journal:  Mol Cell Biol       Date:  1991-02       Impact factor: 4.272

2.  Inhibition of v-Mos kinase activity by protein kinase A.

Authors:  Y Yang; C H Herrmann; R B Arlinghaus; B Singh
Journal:  Mol Cell Biol       Date:  1996-03       Impact factor: 4.272

3.  Effects of the v-mos oncogene on Xenopus development: meiotic induction in oocytes and mitotic arrest in cleaving embryos.

Authors:  R S Freeman; J P Kanki; S M Ballantyne; K M Pickham; D J Donoghue
Journal:  J Cell Biol       Date:  1990-08       Impact factor: 10.539

4.  v-mos proteins encoded by myeloproliferative sarcoma virus and its ts159 mutant.

Authors:  B Singh; C Stocking; R Walker; Y D Yang; W Ostertag; R B Arlinghaus
Journal:  J Virol       Date:  1992-02       Impact factor: 5.103

5.  Mos in the oocyte: how to use MAPK independently of growth factors and transcription to control meiotic divisions.

Authors:  Aude Dupré; Olivier Haccard; Catherine Jessus
Journal:  J Signal Transduct       Date:  2010-12-19
  5 in total

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