Correlation of serum lipids with uric acid and blood sugar in normal males.

In a group of healthy adult males, the correlation of serum triglycerides with cholesterol, uric acid, blood sugar and obesity was not significant. The annual variation of these biochemical determinations was of a sufficient degree to warrant caution in designating an individual as being at risk of developing coronary artery disease on the basis of a single value. Until our knowledge concerning the basic factors predisposing to coronary artery disease is more fully developed, it would appear that multiple biochemical determinations related to lipid, protein and carbohydrate metabolism should be included at repeated intervals in any longitudinal study of this disease process.