Literature DB >> 25283703

Lingual mucosal graft in treatment of Peyronie disease.

Emad A Salem1, Ehab H Elkady1, Ahmed Sakr1, Aref M Maarouf2, Lotfy Bendary1, Salem Khalil1, Ashraf Shahin1, Hussein Kamel1.   

Abstract

OBJECTIVE: To evaluate the use of lingual mucosal graft (LMG) as a substitute for tunica albuginea in the treatment of Peyronie disease (PD). PATIENTS AND METHODS: Seventeen patients, reporting normal erectile function, with PD interfering with sexual function were operated on by plaque excision and grafting with LMG. Preoperative assessment included: the International Index of Erectile Function-5 score, penile duplex, and penile curvature angle measurement. Postoperative erectile function and penile deformity were assessed every 3 months for 9-18 months.
RESULTS: Mean age of the patients was 52 (± 4.7) years and mean angle of deformity was 60° (± 5.1). Donor site complications occurred in the form of mild transient swelling, numbness, and pain. Postoperative assessment showed complete penile straightening in 15 patients with mild curvature recurrence (<20°) in 2 patients at the third month. De novo mild erectile dysfunction was reported by 1 patient who responded to low-dose phosphodiesterase type 5 inhibitor. Patients' and partners' satisfaction was reported in 16 (94%) patients. These results remained stable until the end of the follow-up period.
CONCLUSION: LMG seems to be a valuable substitute for tunica albuginea in cases of PD. It is readily available and shows early graft take. It also proved safety, reliability, feasibility, and a satisfactory short-term outcome for the treatment of PD.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 25283703     DOI: 10.1016/j.urology.2014.07.042

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  6 in total

1.  Penile Sensory Changes After Plaque Incision and Grafting Surgery for Peyronie's Disease.

Authors:  Jean E Terrier; Raanan Tal; Christian J Nelson; John P Mulhall
Journal:  J Sex Med       Date:  2018-09-06       Impact factor: 3.802

2.  The histopathological effects of intracavernosal mitomycin-C injection in a rat Peyronie's disease model.

Authors:  Engin Kaya; Yusuf Kibar; Sercan Yilmaz; Ayhan Ozcan; Burak Kopru; Turgay Ebiloglu; Hasan Cem Irkilata
Journal:  Can Urol Assoc J       Date:  2017-11       Impact factor: 1.862

3.  Microsurgical tunica albuginea transplantation in an animal model.

Authors:  Salvatore Sansalone; Carla Loreto; Rosario Leonardi; Giuseppe Vespasiani; Giuseppe Musumeci; Claudia Lombardo; Sergio Castorina; Venera Cardile; Rosario Caltabiano
Journal:  Asian J Androl       Date:  2017 Nov-Dec       Impact factor: 3.285

Review 4.  Contemporary surgical and non-surgical management of Peyronie's disease.

Authors:  George F Wayne; Billy H Cordon
Journal:  Transl Androl Urol       Date:  2018-08

Review 5.  Grafting techniques for Peyronie's disease.

Authors:  Georgios Hatzichristodoulou
Journal:  Transl Androl Urol       Date:  2016-06

Review 6.  Peyronie's disease: What's around the bend?

Authors:  Aylin N Bilgutay; Alexander W Pastuszak
Journal:  Indian J Urol       Date:  2016 Jan-Mar
  6 in total

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