| Literature DB >> 25281398 |
Abstract
Hendra virus infection of horses occurred sporadically between 1994 and 2010 as a result of spill-over from the viral reservoir in Australian mainland flying-foxes, and occasional onward transmission to people also followed from exposure to affected horses. An unprecedented number of outbreaks were recorded in 2011 leading to heightened community concern. Release of an inactivated subunit vaccine for horses against Hendra virus represents the first commercially available product that is focused on mitigating the impact of a Biosafety Level 4 pathogen. Through preventing the development of acute Hendra virus disease in horses, vaccine use is also expected to reduce the risk of transmission of infection to people. CrownEntities:
Keywords: Disease; Emerging; Hendra; Horse; Infectious; Pathogenesis; Vaccine; Zoonotic
Mesh:
Year: 2014 PMID: 25281398 PMCID: PMC4252762 DOI: 10.1016/j.cveq.2014.08.004
Source DB: PubMed Journal: Vet Clin North Am Equine Pract ISSN: 0749-0739 Impact factor: 1.792