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Literature DB >> 2528123

Statistical analysis of mammalian pre-mRNA splicing sites.

Abstract

222 donor and 222 acceptor (including 206 pairs) non-homologous splicing sites were studied. Well known features of these were confirmed and some novel observations were made. It is (1) cCAGGGag signal in (-60)-(-58) region of acceptor sites; (2) strong complementarity between regions (-69)-(-55) and (-36)-(-22) of some of the acceptor sites, and (3) small but statistically significant correlation between discrimination energies of corresponding donor and acceptor sites.

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Year: 1989 PMID： 2528123 PMCID： PMC318283 DOI： 10.1093/nar/17.15.6369

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

15 in total

1. A role for exon sequences and splice-site proximity in splice-site selection.

Authors: R Reed; T Maniatis
Journal: Cell Date: 1986-08-29 Impact factor: 41.582

2. Globin mRNA sequences: analysis of base pairing and evolutionary implications.

Authors: W Salser
Journal: Cold Spring Harb Symp Quant Biol Date: 1978

3. Syntactic pattern analysis of 5'-splice site sequences of mRNA precursors in higher eukaryote genes.

Authors: M Kudo; Y Iida; M Shimbo
Journal: Comput Appl Biosci Date: 1987-11

Review 4. The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing.

Authors: T Maniatis; R Reed
Journal: Nature Date: 1987 Feb 19-25 Impact factor: 49.962

5. Minimal exon sequence requirements for efficient in vitro splicing of mono-intronic nuclear pre-mRNA.

Authors: A Parent; S Zeitlin; A Efstratiadis
Journal: J Biol Chem Date: 1987-08-15 Impact factor: 5.157

6. Information content of binding sites on nucleotide sequences.

Authors: T D Schneider; G D Stormo; L Gold; A Ehrenfeucht
Journal: J Mol Biol Date: 1986-04-05 Impact factor: 5.469

Review 7. Pre-mRNA splicing.

Authors: M R Green
Journal: Annu Rev Genet Date: 1986 Impact factor: 16.830

8. A minimal intron length but no specific internal sequence is required for splicing the large rabbit beta-globin intron.

Authors: B Wieringa; E Hofer; C Weissmann
Journal: Cell Date: 1984-07 Impact factor: 41.582

9. Prediction of splice junctions in mRNA sequences.

Authors: K Nakata; M Kanehisa; C DeLisi
Journal: Nucleic Acids Res Date: 1985-07-25 Impact factor: 16.971

10. Application of learning techniques to splicing site recognition.

Authors: J Quinqueton; J Moreau
Journal: Biochimie Date: 1985-05 Impact factor: 4.079

13 in total

1. Statistical analysis and prediction of the exonic structure of human genes.

Authors: M S Gelfand
Journal: J Mol Evol Date: 1992-09 Impact factor: 2.395

2. Computer prediction of the exon-intron structure of mammalian pre-mRNAs.

Authors: M S Gelfand
Journal: Nucleic Acids Res Date: 1990-10-11 Impact factor: 16.971

3. In vivo splicing of the beta tropomyosin pre-mRNA: a role for branch point and donor site competition.

Authors: D Libri; L Balvay; M Y Fiszman
Journal: Mol Cell Biol Date: 1992-07 Impact factor: 4.272

4. Expression of the gene encoded by a family of macronuclear chromosomes generated by alternative DNA processing in Oxytricha fallax.

Authors: K R Williams; G Herrick
Journal: Nucleic Acids Res Date: 1991-09-11 Impact factor: 16.971

5. Exon as well as intron sequences are cis-regulating elements for the mutually exclusive alternative splicing of the beta tropomyosin gene.

Authors: D Libri; M Goux-Pelletan; E Brody; M Y Fiszman
Journal: Mol Cell Biol Date: 1990-10 Impact factor: 4.272

6. Nuclear pre-mRNA introns: analysis and comparison of intron sequences from Tetrahymena thermophila and other eukaryotes.

Authors: C Csank; F M Taylor; D W Martindale
Journal: Nucleic Acids Res Date: 1990-09-11 Impact factor: 16.971