Literature DB >> 25280216

Revisiting the flight of Icarus: making human organs from PSCs with large animal chimeras.

Tamir Rashid1, Toshihiro Kobayashi2, Hiromitsu Nakauchi3.   

Abstract

While cell therapies hold great potential for treating many conditions, their utility for treating patients that require whole organ replacement is unclear. To address this challenge, we propose using genetically engineered "organ niches" in large animals to generate human organs from pluripotent stem cells and discuss the hurdles facing such strategies.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 25280216     DOI： 10.1016/j.stem.2014.09.013

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  35 in total

Review 1.  Stem Cells in Skeletal Tissue Engineering: Technologies and Models.

Authors:  Mark T Langhans; Shuting Yu; Rocky S Tuan
Journal:  Curr Stem Cell Res Ther       Date:  2016       Impact factor: 3.828

Review 2.  Stem cells and interspecies chimaeras.

Authors:  Jun Wu; Henry T Greely; Rudolf Jaenisch; Hiromitsu Nakauchi; Janet Rossant; Juan Carlos Izpisua Belmonte
Journal:  Nature       Date:  2016-12-01       Impact factor: 49.962

3.  Hypomorphic phenotype of Foxn1 gene-modified rats by CRISPR/Cas9 system.

Authors:  Teppei Goto; Hiromasa Hara; Hiromitsu Nakauchi; Shinichi Hochi; Masumi Hirabayashi
Journal:  Transgenic Res       Date:  2016-03-02       Impact factor: 2.788

4.  Antibody Conditioning Enables MHC-Mismatched Hematopoietic Stem Cell Transplants and Organ Graft Tolerance.

Authors:  Benson M George; Kevin S Kao; Hye-Sook Kwon; Brenda J Velasco; Jessica Poyser; Angela Chen; Alan C Le; Akanksha Chhabra; Cassandra E Burnett; Devon Cajuste; Malachia Hoover; Kyle M Loh; Judith A Shizuru; Irving L Weissman
Journal:  Cell Stem Cell       Date:  2019-06-13       Impact factor: 24.633

5.  Kidney Regeneration in Later-Stage Mouse Embryos via Transplanted Renal Progenitor Cells.

Authors:  Shuichiro Yamanaka; Yatsumu Saito; Toshinari Fujimoto; Tsuyoshi Takamura; Susumu Tajiri; Kei Matsumoto; Takashi Yokoo
Journal:  J Am Soc Nephrol       Date:  2019-09-23       Impact factor: 10.121

Review 6.  Pancreas regeneration.

Authors:  Qiao Zhou; Douglas A Melton
Journal:  Nature       Date:  2018-05-16       Impact factor: 49.962

Review 7.  Challenging Regeneration to Transform Medicine.

Authors:  Ann Tsukamoto; Stewart E Abbot; Lisa C Kadyk; Natalie D DeWitt; David V Schaffer; Jason A Wertheim; Kevin J Whittlesey; Michael J Werner
Journal:  Stem Cells Transl Med       Date:  2015-11-25       Impact factor: 6.940

Review 8.  Stem cells and genome editing: approaches to tissue regeneration and regenerative medicine.

Authors:  Nozomu Takata; Mototsugu Eiraku
Journal:  J Hum Genet       Date:  2017-10-11       Impact factor: 3.172

9.  Regenerative medicine: Interspecies pancreas transplants.

Authors:  Qiao Zhou
Journal:  Nature       Date:  2017-01-25       Impact factor: 49.962

10.  Interspecies organogenesis generates autologous functional islets.

Authors:  Tomoyuki Yamaguchi; Hideyuki Sato; Megumi Kato-Itoh; Teppei Goto; Hiromasa Hara; Makoto Sanbo; Naoaki Mizuno; Toshihiro Kobayashi; Ayaka Yanagida; Ayumi Umino; Yasunori Ota; Sanae Hamanaka; Hideki Masaki; Sheikh Tamir Rashid; Masumi Hirabayashi; Hiromitsu Nakauchi
Journal:  Nature       Date:  2017-01-25       Impact factor: 49.962
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