Lindsey Culler1, John Whitcomb, Sheri Webster. 1. Lindsey Culler, BSN, RN, is graduated from Clemson University in 2009 with a Bachelor of Science Degree in Nursing. She has worked as a Registered Nurse since graduation on a Telemetry Unit and in the Cardiovascular Step Down and Intensive Care Units. She has recently completed her Master's of Science Degree at Clemson University and looks forward to working as a Family Nurse Practitioner in the future. John Whitcomb, PhD, RN, CCRN, FCCM, is an assistant professor at Clemson University School of Nursing and serves as the Accelerated Second Degree Program coordinator. He is president of the CVCSCCM Chapter and president elect for the South Carolina League of Nurses. His research area is in Resuscitative Outcomes. He is on the Editorial Board for DCCN. Sheri Webster, MSN, RN, CSPI, is an instructor at Clemson University School of Nursing and serves as the lead instructor for Leadership, Management, and Senior Practicum. She is a doctoral student at the University of South Carolina and a Nurse Scholar at the National Jonas Center for Nursing and Veterans Healthcare. Her research is in nursing workforce and the transition of new nurse graduates into nursing practice.
Abstract
BACKGROUND: Coronary artery disease is a major problem in the United States, affecting 785 000 individuals, with the most serious event being a cardiopulmonary arrest. Families of post-cardiac arrest patients are left with difficult decisions to be made. OBJECTIVE: This article is a comprehensive literature review examining the current research available to health care professionals about the biomarker serum neuron-specific enolase (NSE) and its use in predicting neurological outcomes in comatose post-cardiac arrest patients. METHODS: Using the bibliographic databases CINAHL, Plus, EBSCOhost, MEDLINE, PubMed, Google Scholar, H. W. Wilson, Cochrane, and NEXUS, from the period 2003 to 2013, revealed there is minimal research or literature on NSE predicting neurological outcomes post-cardiac arrest. RESULTS: Research on this particular biomarker is relatively new, and more research is necessary to establish an adequate amount of support. At this time, an exact NSE cutoff value or its exact ability to help predict neurological outcomes is unable to be established, and further research is necessary. DISCUSSION: This literature review should provide a basic understanding of NSE and its ability to help predict neurological outcomes of post-cardiac arrest patients earlier. The research provides evidence that NSE should be considered in determining outcomes. However, more research is necessary before nursing practice is changed and implemented into patient care.
BACKGROUND:Coronary artery disease is a major problem in the United States, affecting 785 000 individuals, with the most serious event being a cardiopulmonary arrest. Families of post-cardiac arrestpatients are left with difficult decisions to be made. OBJECTIVE: This article is a comprehensive literature review examining the current research available to health care professionals about the biomarker serum neuron-specific enolase (NSE) and its use in predicting neurological outcomes in comatose post-cardiac arrestpatients. METHODS: Using the bibliographic databases CINAHL, Plus, EBSCOhost, MEDLINE, PubMed, Google Scholar, H. W. Wilson, Cochrane, and NEXUS, from the period 2003 to 2013, revealed there is minimal research or literature on NSE predicting neurological outcomes post-cardiac arrest. RESULTS: Research on this particular biomarker is relatively new, and more research is necessary to establish an adequate amount of support. At this time, an exact NSE cutoff value or its exact ability to help predict neurological outcomes is unable to be established, and further research is necessary. DISCUSSION: This literature review should provide a basic understanding of NSE and its ability to help predict neurological outcomes of post-cardiac arrestpatients earlier. The research provides evidence that NSE should be considered in determining outcomes. However, more research is necessary before nursing practice is changed and implemented into patient care.
Authors: Vineet K Raghu; Christopher M Horvat; Patrick M Kochanek; Ericka L Fink; Robert S B Clark; Panayiotis V Benos; Alicia K Au Journal: Pediatr Crit Care Med Date: 2021-10-01 Impact factor: 3.971
Authors: Roy Cohen; James P Lata; Yurim Lee; Jean C Cruz Hernández; Nozomi Nishimura; Chris B Schaffer; Chinatsu Mukai; Jacquelyn L Nelson; Sharon A Brangman; Yash Agrawal; Alexander J Travis Journal: PLoS One Date: 2015-11-25 Impact factor: 3.240