Literature DB >> 25279926

Inhibition of demethylases by GSK-J1/J4.

Bo Heinemann1, Jesper Morten Nielsen1, Heidi Rye Hudlebusch1, Michael J Lees2, Dorthe Vang Larsen1, Thomas Boesen1, Marc Labelle1, Lars-Ole Gerlach1, Peter Birk1, Kristian Helin3.   

Abstract

Mesh：

Substances：

Year:  2014        PMID： 25279926     DOI： 10.1038/nature13688

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


× No keyword cloud information.
  6 in total

Review 1.  Epigenetic protein families: a new frontier for drug discovery.

Authors:  Cheryl H Arrowsmith; Chas Bountra; Paul V Fish; Kevin Lee; Matthieu Schapira
Journal:  Nat Rev Drug Discov       Date:  2012-04-13       Impact factor: 84.694

Review 2.  Molecular mechanisms and potential functions of histone demethylases.

Authors:  Susanne Marije Kooistra; Kristian Helin
Journal:  Nat Rev Mol Cell Biol       Date:  2012-04-04       Impact factor: 94.444

Review 3.  Chromatin proteins and modifications as drug targets.

Authors:  Kristian Helin; Dashyant Dhanak
Journal:  Nature       Date:  2013-10-24       Impact factor: 49.962

Review 4.  Histone methylation: a dynamic mark in health, disease and inheritance.

Authors:  Eric L Greer; Yang Shi
Journal:  Nat Rev Genet       Date:  2012-04-03       Impact factor: 53.242

Review 5.  Histone lysine demethylases as targets for anticancer therapy.

Authors:  Jonas W Højfeldt; Karl Agger; Kristian Helin
Journal:  Nat Rev Drug Discov       Date:  2013-11-15       Impact factor: 84.694

6.  A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response.

Authors:  Laurens Kruidenier; Chun-wa Chung; Zhongjun Cheng; John Liddle; KaHing Che; Gerard Joberty; Marcus Bantscheff; Chas Bountra; Angela Bridges; Hawa Diallo; Dirk Eberhard; Sue Hutchinson; Emma Jones; Roy Katso; Melanie Leveridge; Palwinder K Mander; Julie Mosley; Cesar Ramirez-Molina; Paul Rowland; Christopher J Schofield; Robert J Sheppard; Julia E Smith; Catherine Swales; Robert Tanner; Pamela Thomas; Anthony Tumber; Gerard Drewes; Udo Oppermann; Dinshaw J Patel; Kevin Lee; David M Wilson
Journal:  Nature       Date:  2012-08-16       Impact factor: 49.962
  6 in total
  80 in total

1.  Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A.

Authors:  John R Horton; Clayton B Woodcock; Qin Chen; Xu Liu; Xing Zhang; John Shanks; Ganesha Rai; Bryan T Mott; Daniel J Jansen; Stephen C Kales; Mark J Henderson; Matthew Cyr; Katherine Pohida; Xin Hu; Pranav Shah; Xin Xu; Ajit Jadhav; David J Maloney; Matthew D Hall; Anton Simeonov; Haian Fu; Paula M Vertino; Xiaodong Cheng
Journal:  J Med Chem       Date:  2018-11-15       Impact factor: 7.446

Review 2.  Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials.

Authors:  Yuan Cheng; Cai He; Manni Wang; Xuelei Ma; Fei Mo; Shengyong Yang; Junhong Han; Xiawei Wei
Journal:  Signal Transduct Target Ther       Date:  2019-12-17

Review 3.  Inhibitors of Protein Methyltransferases and Demethylases.

Authors:  H Ümit Kaniskan; Michael L Martini; Jian Jin
Journal:  Chem Rev       Date:  2017-03-24       Impact factor: 60.622

Review 4.  The role of epigenetics in renal ageing.

Authors:  Paul G Shiels; Dagmara McGuinness; Maria Eriksson; Jeroen P Kooman; Peter Stenvinkel
Journal:  Nat Rev Nephrol       Date:  2017-06-19       Impact factor: 28.314

5.  Inhibition of demethylase KDM6B sensitizes diffuse large B-cell lymphoma to chemotherapeutic drugs.

Authors:  Rohit Mathur; Lalit Sehgal; Ondrej Havranek; Stefan Köhrer; Tamer Khashab; Neeraj Jain; Jan A Burger; Sattva S Neelapu; R Eric Davis; Felipe Samaniego
Journal:  Haematologica       Date:  2016-10-14       Impact factor: 9.941

Review 6.  Targeting Metalloenzymes for Therapeutic Intervention.

Authors:  Allie Y Chen; Rebecca N Adamek; Benjamin L Dick; Cy V Credille; Christine N Morrison; Seth M Cohen
Journal:  Chem Rev       Date:  2018-09-07       Impact factor: 60.622

7.  Kruidenier et al. reply.

Authors:  Laurens Kruidenier; Chun-wa Chung; Zhongjun Cheng; John Liddle; KaHing Che; Gerard Joberty; Marcus Bantscheff; Chas Bountra; Angela Bridges; Hawa Diallo; Dirk Eberhard; Sue Hutchinson; Emma Jones; Roy Katso; Melanie Leveridge; Palwinder K Mander; Julie Mosley; Cesar Ramirez-Molina; Paul Rowland; Christopher J Schofield; Robert J Sheppard; Julia E Smith; Catherine Swales; Robert Tanner; Pamela Thomas; Anthony Tumber; Gerard Drewes; Udo Oppermann; Dinshaw J Patel; Kevin Lee; David M Wilson
Journal:  Nature       Date:  2014-10-02       Impact factor: 49.962

Review 8.  Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX.

Authors:  Kelly Marie Arcipowski; Carlos Alberto Martinez; Panagiotis Ntziachristos
Journal:  Curr Opin Genet Dev       Date:  2016-05-03       Impact factor: 5.578

9.  Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment.

Authors:  Aditi Qamra; Tsz Wai Chu; Mélanie Criqui; Monika Sharma; Julissa Tsao; Danielle A Henry; Dalia Barsyte-Lovejoy; Cheryl H Arrowsmith; Neil Winegarden; Mathieu Lupien; Lea Harrington
Journal:  Elife       Date:  2020-04-16       Impact factor: 8.140

10.  Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity.

Authors:  Carsten Merkwirth; Virginija Jovaisaite; Jenni Durieux; Olli Matilainen; Sabine D Jordan; Pedro M Quiros; Kristan K Steffen; Evan G Williams; Laurent Mouchiroud; Sarah U Tronnes; Virginia Murillo; Suzanne C Wolff; Reuben J Shaw; Johan Auwerx; Andrew Dillin
Journal:  Cell       Date:  2016-04-28       Impact factor: 41.582
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.