Literature DB >> 25278724

Severe reversible myocardial injury associated with aluminium phosphide toxicity: A case report and review of literature.

Wael Elabbassi1, Mohammed Andaleeb Chowdhury2, Arif Al Nooryani Fachtartz1.   

Abstract

Aluminium phosphide is commonly used as an insecticide and can be toxic to humans at the cellular level by interfering with mitochondrial energy metabolism. We report on three cases of severe aluminium phosphide cardio-toxicity, resulting in severe decrease in both ventricular heart functions. The first case succumbed to intractable ventricular arrhythmias complicated by multi-organ failure before she died; while the other two cases required invasive hemodynamic support and eventually improved over the course of 10-14 days. We describe our experience and the challenges faced while managing one of them.

Entities:  

Keywords:  AlP, aluminium phosphide; Aluminium phosphide toxicity; Cardiomyopathy; ECMO, extra corporeal membrane oxygenation; Extra corporal membrane oxygenation (ECMO); FFA, free fatty acid; IABP, intra-aortic balloon pump; Intra-aortic balloon pump; PH3, phosphine

Year:  2013        PMID: 25278724      PMCID: PMC4179901          DOI: 10.1016/j.jsha.2013.11.006

Source DB:  PubMed          Journal:  J Saudi Heart Assoc        ISSN: 1016-7315


  16 in total

Review 1.  Occupational exposure to aluminium phosphide and phosphine gas? A suspected case report and review of the literature.

Authors:  D L Sudakin
Journal:  Hum Exp Toxicol       Date:  2005-01       Impact factor: 2.903

Review 2.  Aluminium phosphide poisoning.

Authors:  R G Bogle; P Theron; P Brooks; P I Dargan; J Redhead
Journal:  Emerg Med J       Date:  2006-01       Impact factor: 2.740

3.  Cardiovascular manifestations in aluminium phosphide poisoning with special reference to echocardiographic changes.

Authors:  M S Gupta; A Malik; V K Sharma
Journal:  J Assoc Physicians India       Date:  1995-11

4.  Histopathological changes in aluminium phosphide poisoning.

Authors:  B Arora; R S Punia; R Kalra; S N Chugh; D R Arora
Journal:  J Indian Med Assoc       Date:  1995-10

5.  Electrocardiographic abnormalities in aluminium phosphide poisoning with special reference to its incidence, pathogenesis, mortality and histopathology.

Authors:  S N Chugh; K Chugh; S Ram; K C Malhotra
Journal:  J Indian Med Assoc       Date:  1991-02

6.  Effect of aluminium phosphide exposure on kinetic properties of cytochrome oxidase and mitochondrial energy metabolism in rat brain.

Authors:  Raina Dua; Kiran D Gill
Journal:  Biochim Biophys Acta       Date:  2004-09-06

7.  Efficacy of magnesium sulphate in aluminium phosphide poisoning--comparison of two different dose schedules.

Authors:  S N Chugh; P Kumar; H K Aggarwal; A Sharma; S K Mahajan; K C Malhotra
Journal:  J Assoc Physicians India       Date:  1994-05

8.  Effects of L-carnitine administration on left ventricular remodeling after acute anterior myocardial infarction: the L-Carnitine Ecocardiografia Digitalizzata Infarto Miocardico (CEDIM) Trial.

Authors:  S Iliceto; D Scrutinio; P Bruzzi; G D'Ambrosio; L Boni; M Di Biase; G Biasco; P G Hugenholtz; P Rizzon
Journal:  J Am Coll Cardiol       Date:  1995-08       Impact factor: 24.094

9.  Cardiac arrhythmias in aluminium phosphide poisoning studied by on continuous holter and cardioscopic monitoring.

Authors:  S B Siwach; H Singh; V K Katyal; G Bhardwaj
Journal:  J Assoc Physicians India       Date:  1998-07

10.  Serum & tissue magnesium content in patients of aluminium phosphide poisoning and critical evaluation of high dose magnesium sulphate therapy in reducing mortality.

Authors:  S B Siwach; P Singh; S Ahlawat; A Dua; D Sharma
Journal:  J Assoc Physicians India       Date:  1994-02
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  8 in total

1.  Diagnosis of aluminum phosphide poisoning using a new analytical approach: forensic application to a lethal intoxication.

Authors:  Hui Yan; Ping Xiang; Sujing Zhang; Baohua Shen; Min Shen
Journal:  Int J Legal Med       Date:  2017-02-27       Impact factor: 2.686

2.  The Role of Echocardiographic Findings in Estimating Survival Probability of Intensive Care Unit Admitted Aluminum Phosphide Poisoned Patients.

Authors:  Fatma M Elgazzar; Mohamed A Shama; Osama Shoeib; Amal S A F Hafez
Journal:  J Med Toxicol       Date:  2022-01-27

3.  STEMI in Young Befogged by Aluminum Phosphide Toxicity-Role of ECMO as Salvage Therapy and Trimetazidine and Magnesium to Suppress Arrhythmias.

Authors:  Chaitra C Rao; Gunavanthi Jayakumar Himaaldev
Journal:  Indian J Crit Care Med       Date:  2020-08

4.  A study of the predictive factors of mortality in acute poisoning with aluminum phosphide with special reference to echocardiography and SOFA score.

Authors:  Abeer A Sheta; Asmaa S El-Banna; Rania Abd Elmeguid; Hany E Mohamed; Nehad H Gad
Journal:  Environ Sci Pollut Res Int       Date:  2019-09-13       Impact factor: 4.223

5.  The impact of severity of initial illness, determined by SOFA score, and presence of anemia on outcomes among patients requiring Extra Corporal Membrane Oxygenation (ECMO) support: A single center experience.

Authors:  Wael Elabbassi; Farah Al Aila; Mohammed Andaleeb Chowdhury; Ahmed Najib; H Zaid; M Michelin; Arif Al Nooryani
Journal:  Indian Heart J       Date:  2017-05-12

6.  Reversible Myocardial Injury and Intraventricular Thrombus Associated with Aluminium Phosphide Poisoning.

Authors:  Abdelkader Jalil El Hangouche; Hala Fennich; Oumaima Alaika; Taoufiq Dakka; Zaineb Raissouni; Latifa Oukerraj; Nawal Doghmi; Mohamed Cherti
Journal:  Case Rep Cardiol       Date:  2017-04-09

7.  Changes of QT Dispersion in Patients Suffering from Aluminium Phosphide Poisoning (Rice Pill).

Authors:  Ali Eshraghi; Niloofar Rajaei; Mahdi Balali Mood; Vida Vakili; Javad Ramezani
Journal:  Open Access Maced J Med Sci       Date:  2019-07-20

8.  Outcome of patients supported by extracorporeal membrane oxygenation for aluminum phosphide poisoning: An observational study.

Authors:  Bishav Mohan; Bhupinder Singh; Vivek Gupta; Sarju Ralhan; Dinesh Gupta; Sandeep Puri; Abhishek Goyal; Naved Aslam; Rohit Tandon; Gurpreet Singh Wander
Journal:  Indian Heart J       Date:  2016-04-11
  8 in total

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