Literature DB >> 25276689

Down syndrome screening methods in Iranian pregnant women.

Azizeh Farshbaf Khalili1, Mahnaz Shahnazi2, Khadijeh Hajizadeh3, Mahmoud Shekari Khaniani4.   

Abstract

INTRODUCTION: Down syndrome is one of the most prevalent genetic diseases. Screening methods for this syndrome are easy and safe and are recommended to all pregnant women particularly mothers over 35 years of age. This study aimed to review the status of Down syndrome screening and related factors in Iranian pregnant women.
METHODS: This descriptive analytical study was carried out in 2011. It included 400 women who were randomly selected from those referring to Alzahra Hospital (Tabriz, Iran) during their third trimester of pregnancy. Data was collected through a question-naire whose reliability and validity have been approved. The data was analyzed by chi-square test in SPSS13.
RESULTS: The results showed that while 28 and 26 women imple-mented screening tests during the first and second trimesters, respectively, only 5 sub-jects benefited from both (integrated test). Chi-square test showed significant correla-tions between the implementation of screening methods and age, education level, in-come, and the location of prenatal care (p < 0.05).
CONCLUSION: The findings of the present study showed women to poorly implement Down syndrome screening methods. Therefore, the necessity of providing appropriate educational programs for health staff and mothers seems undeniable. Moreover, paying attention to the related factors such as income, educational level, and adequate training of mothers during pregnancy is essential.

Entities:  

Keywords:  Down syndrome; Pregnancy; Screening methods

Year:  2012        PMID: 25276689      PMCID: PMC4161074          DOI: 10.5681/jcs.2012.021

Source DB:  PubMed          Journal:  J Caring Sci        ISSN: 2251-9920


  6 in total

1.  Antenatal screening for Down's syndrome with the quadruple test.

Authors:  Nicholas J Wald; Wayne J Huttly; Allan K Hackshaw
Journal:  Lancet       Date:  2003-03-08       Impact factor: 79.321

Review 2.  Wrongful deaths and rightful lives - screening for Down syndrome.

Authors:  Frank Buckley; Sue Buckley
Journal:  Downs Syndr Res Pract       Date:  2008-10

3.  A study protocol of a randomised controlled trial to investigate if a community based strength training programme improves work task performance in young adults with Down syndrome.

Authors:  Nora Shields; Nicholas F Taylor; Bo Fernhall
Journal:  BMC Pediatr       Date:  2010-03-25       Impact factor: 2.125

4.  Alzheimer's disease amyloid-beta links lens and brain pathology in Down syndrome.

Authors:  Juliet A Moncaster; Roberto Pineda; Robert D Moir; Suqian Lu; Mark A Burton; Joy G Ghosh; Maria Ericsson; Stephanie J Soscia; Anca Mocofanescu; Rebecca D Folkerth; Richard M Robb; Jer R Kuszak; John I Clark; Rudolph E Tanzi; David G Hunter; Lee E Goldstein
Journal:  PLoS One       Date:  2010-05-20       Impact factor: 3.240

Review 5.  First- and second-trimester Down syndrome screening: current strategies and clinical guidelines.

Authors:  Sheng-Wen Shaw; Jenn-Jeih Hsu; Chien-Nan Lee; Ching-Hua Hsiao; Chih-Ping Chen; T'sang-T'ang Hsieh; Po-Jen Cheng
Journal:  Taiwan J Obstet Gynecol       Date:  2008-06       Impact factor: 1.705

Review 6.  Clinical practice. The care of children with Down syndrome.

Authors:  Michel E Weijerman; J Peter de Winter
Journal:  Eur J Pediatr       Date:  2010-07-15       Impact factor: 3.183

  6 in total

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