Literature DB >> 25276081

Augmentation of filtering blebs with viscoelastics in trabeculectomy.

Hyerin Jeong1, Kyung Rim Sung1.   

Abstract

PURPOSE: To evaluate the clinical outcome of viscoelastics (VE, sodium hyaluronate)-augmented trabeculectomy (VAT, 66 eyes) and conventional trabeculectomy (CT, 57 eyes) for glaucomatous eyes.
METHODS: In the VAT group, half of the anterior chamber space was filled with VE via the paracentesis site at the end of CT and a balanced salt solution was injected into the anterior chamber. This procedure induced migration of VE from the anterior chamber into the bleb space; thus the bleb was elevated with underlying VE. Follow-up examinations were performed until 1 year after surgery. Success was defined as the attainment of an intraocular pressure (IOP) greater than 5 mmHg and less than 22 mmHg. If IOP was in the range of success without antiglaucoma medication, it was regarded as a complete success.
RESULTS: The mean postoperative IOP was significantly lower in the VAT group at postoperative 1 day, 1 week, and 1 month. The complete success rate was significantly higher in the VAT group (89%) than in the CT group (75%), though the qualified success rate was not different between the two groups. The number of IOP-lowering medications at postoperative 1 year was significantly higher in the CT group (1.30 ± 1.08 vs. 0.73 ± 0.98, p = 0.003). Among postoperative procedures, laser suture lysis was required less frequently in the VAT group (p < 0.001).
CONCLUSIONS: Placing VE within the bleb at the end of surgery may result in better IOP control and less need for IOP-lowering medication without any additional materials, cost, or time.

Entities:  

Keywords:  Anti-fibrotic agent; Glaucoma; Hyaluronic acid; Trabeculectomy; Viscoelastics

Mesh:

Substances:

Year:  2014        PMID: 25276081      PMCID: PMC4179116          DOI: 10.3341/kjo.2014.28.5.393

Source DB:  PubMed          Journal:  Korean J Ophthalmol        ISSN: 1011-8942


  16 in total

1.  Combined perfluoropropane gas and viscoelastic material injection for anterior chamber reformation following trabeculectomy.

Authors:  S Kurtz; I Leibovitch
Journal:  Br J Ophthalmol       Date:  2002-11       Impact factor: 4.638

2.  Early postoperative prognostic indicators following trabeculectomy.

Authors:  W C Stewart; M B Shields; K N Miller; M Blasini; S E Sutherland
Journal:  Ophthalmic Surg       Date:  1991-01

3.  The effect of hyaluronic acid-carboxymethylcellulose in reducing adhesion reformation in rabbits.

Authors:  H Osada; M Minai; I Tsunoda; T K Fujii; K Tsubata; K Satoh
Journal:  J Int Med Res       Date:  1999       Impact factor: 1.671

4.  Hyaluronic acid-carboxymethylcellulose film and perianastomotic adhesions in previously irradiated rats.

Authors:  D Bowers; R B Raybon; C R Wheeless
Journal:  Am J Obstet Gynecol       Date:  1999-12       Impact factor: 8.661

Review 5.  Preclinical evaluation of Seprafilm bioresorbable membrane.

Authors:  J W Burns; M J Colt; L S Burgees; K C Skinner
Journal:  Eur J Surg Suppl       Date:  1997

6.  Stabilization of post-trabeculectomy flat anterior chamber with Healon and sulfur hexafluoride.

Authors:  Orna Geyer; Eitan Segev; Jordan M Steinberg; Gila Buckman
Journal:  J Cataract Refract Surg       Date:  2003-10       Impact factor: 3.351

Review 7.  Dysfunctional filtering blebs.

Authors:  A Azuara-Blanco; L J Katz
Journal:  Surv Ophthalmol       Date:  1998 Sep-Oct       Impact factor: 6.048

8.  Solid hyaluronic acid film and the prevention of postoperative fibrous scar formation in experimental animal eyes.

Authors:  Kimio Takeuchi; Mitsuru Nakazawa; Hitoshi Yamazaki; Yasuhiro Miyagawa; Tadashi Ito; Futoshi Ishikawa; Tomomi Metoki
Journal:  Arch Ophthalmol       Date:  2009-04

9.  Seprafilm as a new antifibrotic agent following trabeculectomy in rabbit eyes.

Authors:  Naoshi Tsurumaru; Mikki Arai; Kenichi Teruya; Jun Sueda; Ryoji Yamakawa
Journal:  Jpn J Ophthalmol       Date:  2009-03-31       Impact factor: 2.447

Review 10.  Management of complications in glaucoma surgery.

Authors:  Lingam Vijaya; Panday Manish; George Ronnie; B Shantha
Journal:  Indian J Ophthalmol       Date:  2011-01       Impact factor: 1.848

View more
  2 in total

1.  Viscoelastic-augmented trabeculectomy: A newer concept.

Authors:  Meghna Solanki; Ankur Kumar; Anubhav Upadhyay; Kishor Kumar
Journal:  Indian J Ophthalmol       Date:  2017-08       Impact factor: 1.848

2.  Comment on: Viscoelastic-augmented trabeculectomy - A newer concept.

Authors:  Sanjay Kumar Daulat Thakur
Journal:  Indian J Ophthalmol       Date:  2018-04       Impact factor: 1.848

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.