Literature DB >> 25270953

Cancer: Lipid kinase PIP5K1α as a new target in prostate cancer.

Alexandra Flemming.   

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Year:  2014        PMID： 25270953     DOI： 10.1038/nrd4446

Source DB:  PubMed          Journal:  Nat Rev Drug Discov        ISSN： 1474-1776            Impact factor:   84.694


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  1 in total

1.  The role of PI3K/AKT-related PIP5K1α and the discovery of its selective inhibitor for treatment of advanced prostate cancer.

Authors:  Julius Semenas; Andreas Hedblom; Regina R Miftakhova; Martuza Sarwar; Rikard Larsson; Liliya Shcherbina; Martin E Johansson; Pirkko Härkönen; Olov Sterner; Jenny L Persson
Journal:  Proc Natl Acad Sci U S A       Date:  2014-07-28       Impact factor: 11.205
  1 in total
  4 in total

1.  FcγRIIIa receptor interacts with androgen receptor and PIP5K1α to promote growth and metastasis of prostate cancer.

Authors:  Per Flodbring Larsson; Richard Karlsson; Martuza Sarwar; Regina Miftakhova; Tianyan Wang; Azharuddin Sajid Syed Khaja; Julius Semenas; Sa Chen; Andreas Hedblom; Amjad Ali; Kristina Ekström-Holka; Athanasios Simoulis; Anjani Kumar; Anette Gjörloff Wingren; Brian Robinson; Sun Nyunt Wai; Nigel P Mongan; David M Heery; Daniel Öhlund; Thomas Grundström; Niels Ødum; Jenny L Persson
Journal:  Mol Oncol       Date:  2022-01-23       Impact factor: 7.449

2.  Targeted inhibition of ERα signaling and PIP5K1α/Akt pathways in castration-resistant prostate cancer.

Authors:  Julius Semenas; Tianyan Wang; Azharuddin Sajid Syed Khaja; Akm Firoj Mahmud; Athanasios Simoulis; Thomas Grundström; Maria Fällman; Jenny L Persson
Journal:  Mol Oncol       Date:  2020-12-16       Impact factor: 6.603

3.  PIP5K1α is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer.

Authors:  Tianyan Wang; Martuza Sarwar; Jonathan B Whitchurch; Hilary M Collins; Tami Green; Julius Semenas; Amjad Ali; Christopher J Roberts; Ryan D Morris; Madlen Hubert; Sa Chen; Zahra El-Schich; Anette G Wingren; Thomas Grundström; Richard Lundmark; Nigel P Mongan; Lena Gunhaga; David M Heery; Jenny L Persson
Journal:  Front Cell Dev Biol       Date:  2022-03-21

4.  Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells.

Authors:  Martuza Sarwar; Julius Semenas; Regina Miftakhova; Athanasios Simoulis; Brian Robinson; Anette Gjörloff Wingren; Nigel P Mongan; David M Heery; Heather Johnsson; Per-Anders Abrahamsson; Nishtman Dizeyi; Jun Luo; Jenny L Persson
Journal:  Oncotarget       Date:  2016-09-27
  4 in total

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