Literature DB >> 25270716

WNT signaling in bone development and homeostasis.

Zhendong Zhong1, Nicole J Ethen, Bart O Williams.   

Abstract

The balance between bone formation and bone resorption controls postnatal bone homeostasis. Research over the last decade has provided a vast amount of evidence that WNT signaling plays a pivotal role in regulating this balance. Therefore, understanding how the WNT signaling pathway regulates skeletal development and homeostasis is of great value for human skeletal health and disease.
© 2014 Wiley Periodicals, Inc.

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Year:  2014        PMID: 25270716      PMCID: PMC4199871          DOI: 10.1002/wdev.159

Source DB:  PubMed          Journal:  Wiley Interdiscip Rev Dev Biol        ISSN: 1759-7684            Impact factor:   5.814


  98 in total

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8.  Wntless spatially regulates bone development through β-catenin-dependent and independent mechanisms.

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