Literature DB >> 25270156

Ocular toxoplasmosis: a very rare presentation in an immunocompetent patient.

Margarida Matias1, Antonia Gomes1, Tiago Marques1, Ana Claudia Fonseca1.   

Abstract

A 28-year-old man presented with a 2-week history of red eye, photophobia, pain and decreased visual acuity of the right eye. The ophthalmological examination revealed hypertensive non-granulomatous panuveitis, retinal vasculitis with focus of retinochoroiditis with pigmented central area suggestive of ocular toxoplasmosis in the active phase. He started treatment with azithromycin, pyrimethamine, topical steroids and measures for control of intraocular pressure. Serology for Toxoplasma gondii was positive and for HIV, negative. For headache and vomiting, he was hospitalised in order to exclude cerebral toxoplasma. The cerebral CT scan, MRI and lumbar puncture were negative and treatment was changed to pyrimethamine, sulfadiazine and prednisolone. For persistence of vomiting he started clindamycin with clinical and ophthalmological improvement. The patient is currently under prophylaxis with co-trimoxazol for 1 year, and maintains clinical improvement. This case illustrates the rarity of presentation of ocular toxoplasmosis, without cerebral in an immunocompetent patient. 2014 BMJ Publishing Group Ltd.

Entities:  

Mesh:

Year:  2014        PMID: 25270156      PMCID: PMC4180574          DOI: 10.1136/bcr-2014-205846

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  4 in total

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Authors:  P D Glasner; C Silveira; D Kruszon-Moran; M C Martins; M Burnier Júnior; S Silveira; M E Camargo; R B Nussenblatt; R A Kaslow; R Belfort Júnior
Journal:  Am J Ophthalmol       Date:  1992-08-15       Impact factor: 5.258

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Authors:  E S Perkins
Journal:  Br J Ophthalmol       Date:  1973-01       Impact factor: 4.638

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Authors:  J V Ongkosuwito; E H Bosch-Driessen; A Kijlstra; A Rothova
Journal:  Am J Ophthalmol       Date:  1999-10       Impact factor: 5.258

4.  Trimethoprim-sulfamethoxazole therapy for ocular toxoplasmosis.

Authors:  E M Opremcak; D K Scales; M R Sharpe
Journal:  Ophthalmology       Date:  1992-06       Impact factor: 12.079

  4 in total
  2 in total

1.  Up-regulated TLR2 and TLR4 expressions in liver and spleen during acute murine T. gondii infection.

Authors:  Jialing Peng; Xiancan Lin; Hongchun Lin; Shengjie Chen; Jinfeng Liu; Zexin Guo; Yuqing Liang; Shiguang Huang; Fangli Lu
Journal:  Parasitol Res       Date:  2016-08-17       Impact factor: 2.289

2.  Spinal cord toxoplasmosis in a young immunocompetent patient.

Authors:  M Martinot; V Greigert; C Farnarier; M L Dardé; C Piperoglou; M Mohseni-Zadeh; J Tarabeux; A Guffroy; O Villard; F Vely
Journal:  Infection       Date:  2019-12-09       Impact factor: 3.553

  2 in total

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