Literature DB >> 2526957

Serotonin function in panic disorder: effect of 1-5-hydroxytryptophan in patients and controls.

H G Westenberg1, J A den Boer.   

Abstract

The responsivity of the serotonergic system to 5-hydroxytryptophan (5-HTP) administration was investigated in seven patients with panic disorder and seven healthy controls. Using cortisol and beta-endorphin as hormonal probes, no evidence was obtained for a dysfunction of the serotonin system in patients. Behaviorally, controls responded differently from patients, in that controls seemed to be more sensitive to 5-HTP. None of the subjects reported an increase in anxiety.

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Year:  1989        PMID： 2526957     DOI： 10.1007/bf00444706

Source DB:  PubMed          Journal:  Psychopharmacology (Berl)        ISSN： 0033-3158            Impact factor:   4.530


  12 in total

1.  Neuroendocrine evidence for serotonin receptor hypersensitivity in panic disorder.

Authors:  R S Kahn; G M Asnis; S Wetzler; H M van Praag
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

2.  Biphasic effect of L-5-HTP in the Vogel conflict model.

Authors:  S Hjorth; B Söderpalm; J A Engel
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

3.  Serotonin function in anxiety. II. Effects of the serotonin agonist MCPP in panic disorder patients and healthy subjects.

Authors:  D S Charney; S W Woods; W K Goodman; G R Heninger
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

4.  Effect of serotonin uptake inhibitors in anxiety disorders; a double-blind comparison of clomipramine and fluvoxamine.

Authors:  J A den Boer; H G Westenberg; W D Kamerbeek; W M Verhoeven; R S Kahn
Journal:  Int Clin Psychopharmacol       Date:  1987-01       Impact factor: 1.659

5.  Effect of a serotonin precursor and uptake inhibitor in anxiety disorders; a double-blind comparison of 5-hydroxytryptophan, clomipramine and placebo.

Authors:  R S Kahn; H G Westenberg; W M Verhoeven; C C Gispen-de Wied; W D Kamerbeek
Journal:  Int Clin Psychopharmacol       Date:  1987-01       Impact factor: 1.659

6.  Enhanced serum cortisol response to 5-hydroxytryptophan in depression and mania.

Authors:  H Y Meltzer; B Uberkoman-Wiita; A Robertson; B J Tricou; M Lowy
Journal:  Life Sci       Date:  1983-12-19       Impact factor: 5.037

7.  Serotoninergic agonists increase plasma levels of beta-endorphin and beta-lipotropin in humans.

Authors:  F Petraglia; F Facchinetti; E Martignoni; G Nappi; A Volpe; A R Genazzani
Journal:  J Clin Endocrinol Metab       Date:  1984-12       Impact factor: 5.958

8.  Lactate provocation of panic attacks. I. Clinical and behavioral findings.

Authors:  M R Liebowitz; A J Fyer; J M Gorman; D Dillon; I L Appleby; G Levy; S Anderson; M Levitt; M Palij; S O Davies
Journal:  Arch Gen Psychiatry       Date:  1984-08

9.  L-5-hydroxytryptophan in the treatment of anxiety disorders.

Authors:  R S Kahn; H G Westenberg
Journal:  J Affect Disord       Date:  1985 Mar-Apr       Impact factor: 4.839

10.  Effect of a serotonin and noradrenaline uptake inhibitor in panic disorder; a double-blind comparative study with fluvoxamine and maprotiline.

Authors:  J A Den Boer; H G Westenberg
Journal:  Int Clin Psychopharmacol       Date:  1988-01       Impact factor: 1.659
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  3 in total

1.  Serotonin function in panic disorder: a double blind placebo controlled study with fluvoxamine and ritanserin.

Authors:  J A Den Boer; H G Westenberg
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

2.  L-5-hydroxytryptophan resets the circadian locomotor activity rhythm of the nocturnal Indian pygmy field mouse, Mus terricolor.

Authors:  Priyoneel Basu; Muniyandi Singaravel; Chandana Haldar
Journal:  Naturwissenschaften       Date:  2012-02-14

Review 3.  Panic disorder. Pathophysiology and drug treatment.

Authors:  M R Johnson; R B Lydiard; J C Ballenger
Journal:  Drugs       Date:  1995-03       Impact factor: 9.546
  3 in total

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