Literature DB >> 25269553

Time cells in the hippocampus: a new dimension for mapping memories.

Howard Eichenbaum1.   

Abstract

Recent studies have revealed the existence of hippocampal neurons that fire at successive moments in temporally structured experiences. Several studies have shown that such temporal coding is not attributable to external events, specific behaviours or spatial dimensions of an experience. Instead, these cells represent the flow of time in specific memories and have therefore been dubbed 'time cells'. The firing properties of time cells parallel those of hippocampal place cells; time cells thus provide an additional dimension that is integrated with spatial mapping. The robust representation of both time and space in the hippocampus suggests a fundamental mechanism for organizing the elements of experience into coherent memories.

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Year:  2014        PMID: 25269553      PMCID: PMC4348090          DOI: 10.1038/nrn3827

Source DB:  PubMed          Journal:  Nat Rev Neurosci        ISSN: 1471-003X            Impact factor:   34.870


  100 in total

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6.  Temporal order judgments activate temporal parietal junction.

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Journal:  J Neurosci       Date:  2009-08-05       Impact factor: 6.167

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Journal:  Nat Neurosci       Date:  2013-02-10       Impact factor: 24.884

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  183 in total

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7.  Time Cells in the Hippocampus Are Neither Dependent on Medial Entorhinal Cortex Inputs nor Necessary for Spatial Working Memory.

Authors:  Marta Sabariego; Antonia Schönwald; Brittney L Boublil; David T Zimmerman; Siavash Ahmadi; Nailea Gonzalez; Christian Leibold; Robert E Clark; Jill K Leutgeb; Stefan Leutgeb
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Review 8.  Navigating Social Space.

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9.  Altered Global Signal Topography and Its Different Regional Localization in Motor Cortex and Hippocampus in Mania and Depression.

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10.  Persistent modifications of hippocampal synaptic function during remote spatial memory.

Authors:  Alice Pavlowsky; Emma Wallace; André A Fenton; Juan Marcos Alarcon
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