Selenium supplementation for the primary prevention of cardiovascular disease.

This is the protocol for a review and there is no abstract. The objectives are as follows: The primary objective is to determine the effectiveness of selenium only supplementation for the primary prevention of CVD. We will also determine potential adverse effects of selenium only supplementation on major CVD risk factors, such as blood pressure, blood lipids and type 2 diabetes. Results will be stratified by baseline selenium status and country where possible, as well as by selenium dosage.