Literature DB >> 25267404

WildCARDs: inflammatory caspases directly detect LPS.

Jon Alan Hagar1, Youssef Aachoui1, Edward Axel Miao1.   

Abstract

Inflammasomes are sensors that serve as activation platforms for caspase-1 - a mechanism that set the prevailing paradigm for inflammatory caspase activation. A recent Nature paper by Shi et al. upends this paradigm by describing an unprecedented model for caspase activation whereby caspase-4, -5, and -11 directly bind their agonist, cytosolic LPS, triggering auto-activation and subsequent pyroptotic cell death.

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Year:  2014        PMID： 25267404      PMCID： PMC4650564          DOI： 10.1038/cr.2014.128

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  11 in total

1.  Non-canonical inflammasome activation targets caspase-11.

Authors:  Nobuhiko Kayagaki; Søren Warming; Mohamed Lamkanfi; Lieselotte Vande Walle; Salina Louie; Jennifer Dong; Kim Newton; Yan Qu; Jinfeng Liu; Sherry Heldens; Juan Zhang; Wyne P Lee; Merone Roose-Girma; Vishva M Dixit
Journal:  Nature       Date:  2011-10-16       Impact factor: 49.962

2.  The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex.

Authors:  Beom Seok Park; Dong Hyun Song; Ho Min Kim; Byong-Seok Choi; Hayyoung Lee; Jie-Oh Lee
Journal:  Nature       Date:  2009-03-01       Impact factor: 49.962

3.  Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens.

Authors:  Leigh A Knodler; Shauna M Crowley; Ho Pan Sham; Hyungjun Yang; Marie Wrande; Caixia Ma; Robert K Ernst; Olivia Steele-Mortimer; Jean Celli; Bruce A Vallance
Journal:  Cell Host Microbe       Date:  2014-08-13       Impact factor: 21.023

4.  Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS.

Authors:  Danielle M Pilla; Jon A Hagar; Arun K Haldar; Ashley K Mason; Daniel Degrandi; Klaus Pfeffer; Robert K Ernst; Masahiro Yamamoto; Edward A Miao; Jörn Coers
Journal:  Proc Natl Acad Sci U S A       Date:  2014-04-08       Impact factor: 11.205

5.  Inflammatory caspases are innate immune receptors for intracellular LPS.

Authors:  Jianjin Shi; Yue Zhao; Yupeng Wang; Wenqing Gao; Jingjin Ding; Peng Li; Liyan Hu; Feng Shao
Journal:  Nature       Date:  2014-08-06       Impact factor: 49.962

6.  Noncanonical inflammasome activation by intracellular LPS independent of TLR4.

Authors:  Nobuhiko Kayagaki; Michael T Wong; Irma B Stowe; Sree Ranjani Ramani; Lino C Gonzalez; Sachiko Akashi-Takamura; Kensuke Miyake; Juan Zhang; Wyne P Lee; Artur Muszyński; Lennart S Forsberg; Russell W Carlson; Vishva M Dixit
Journal:  Science       Date:  2013-07-25       Impact factor: 47.728

7.  Caspase-11 protects against bacteria that escape the vacuole.

Authors:  Youssef Aachoui; Irina A Leaf; Jon A Hagar; Mary F Fontana; Cristine G Campos; Daniel E Zak; Michael H Tan; Peggy A Cotter; Russell E Vance; Alan Aderem; Edward A Miao
Journal:  Science       Date:  2013-01-24       Impact factor: 47.728

8.  The Shigella OspC3 effector inhibits caspase-4, antagonizes inflammatory cell death, and promotes epithelial infection.

Authors:  Taira Kobayashi; Michinaga Ogawa; Takahito Sanada; Hitomi Mimuro; Minsoo Kim; Hiroshi Ashida; Reiko Akakura; Mitsutaka Yoshida; Magdalena Kawalec; Jean-Marc Reichhart; Tsunehiro Mizushima; Chihiro Sasakawa
Journal:  Cell Host Microbe       Date:  2013-05-15       Impact factor: 21.023

9.  Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock.

Authors:  Jon A Hagar; Daniel A Powell; Youssef Aachoui; Robert K Ernst; Edward A Miao
Journal:  Science       Date:  2013-09-13       Impact factor: 47.728

10.  Caspase-11 is expressed in the colonic mucosa and protects against dextran sodium sulfate-induced colitis.

Authors:  D Demon; A Kuchmiy; A Fossoul; Q Zhu; T-D Kanneganti; M Lamkanfi
Journal:  Mucosal Immunol       Date:  2014-05-21       Impact factor: 7.313
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  6 in total

1.  Pyroptosis as a Regulated Form of Necrosis: PI+/Annexin V-/High Caspase 1/Low Caspase 9 Activity in Cells = Pyroptosis?

Authors:  Jun-Ichi Abe; Craig Morrell
Journal:  Circ Res       Date:  2016-05-13       Impact factor: 17.367

Review 2.  Flow signaling and atherosclerosis.

Authors:  Nhat-Tu Le; Uday G Sandhu; Raymundo A Quintana-Quezada; Nguyet Minh Hoang; Keigi Fujiwara; Jun-Ichi Abe
Journal:  Cell Mol Life Sci       Date:  2016-12-30       Impact factor: 9.261

3.  Synthetic glycan-based TLR4 agonists targeting caspase-4/11 for the development of adjuvants and immunotherapeutics.

Authors:  Florian Adanitsch; Jianjin Shi; Feng Shao; Rudi Beyaert; Holger Heine; Alla Zamyatina
Journal:  Chem Sci       Date:  2018-03-15       Impact factor: 9.825

Review 4.  Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways.

Authors:  Alla Zamyatina; Holger Heine
Journal:  Front Immunol       Date:  2020-11-27       Impact factor: 7.561

5.  Modeling the Regulatory Mechanisms by Which NLRX1 Modulates Innate Immune Responses to Helicobacter pylori Infection.

Authors:  Casandra W Philipson; Josep Bassaganya-Riera; Monica Viladomiu; Barbara Kronsteiner; Vida Abedi; Stefan Hoops; Pawel Michalak; Lin Kang; Stephen E Girardin; Raquel Hontecillas
Journal:  PLoS One       Date:  2015-09-14       Impact factor: 3.240

Review 6.  Aminosugar-based immunomodulator lipid A: synthetic approaches.

Authors:  Alla Zamyatina
Journal:  Beilstein J Org Chem       Date:  2018-01-04       Impact factor: 2.883
  6 in total

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