| Literature DB >> 2526637 |
Abstract
The triggering requirements of T cells differ for primed and unprimed cells: primed T cells can be triggered to produce lymphokines without viable antigen-presenting cells (APCs), apparently by crosslinking the T-cell receptor (TCR). Unprimed T cells do, however, require viable APCs and here Jonathan Sprent and Mary Schaefer review what type of cells can carry out this function, with particular reference to APCs for unprimed CD8+ cells.Mesh:
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Year: 1989 PMID: 2526637 DOI: 10.1016/0167-5699(89)90060-1
Source DB: PubMed Journal: Immunol Today ISSN: 0167-5699