Literature DB >> 2526637

Antigen-presenting cells for unprimed T cells.

J Sprent, M Schaefer.   

Abstract

The triggering requirements of T cells differ for primed and unprimed cells: primed T cells can be triggered to produce lymphokines without viable antigen-presenting cells (APCs), apparently by crosslinking the T-cell receptor (TCR). Unprimed T cells do, however, require viable APCs and here Jonathan Sprent and Mary Schaefer review what type of cells can carry out this function, with particular reference to APCs for unprimed CD8+ cells.

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Year:  1989        PMID: 2526637     DOI: 10.1016/0167-5699(89)90060-1

Source DB:  PubMed          Journal:  Immunol Today        ISSN: 0167-5699


  15 in total

1.  Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells.

Authors:  V Bronte; E Apolloni; A Cabrelle; R Ronca; P Serafini; P Zamboni; N P Restifo; P Zanovello
Journal:  Blood       Date:  2000-12-01       Impact factor: 22.113

2.  Mechanisms of recrudescence of Mycobacterium bovis BCG infection in mice.

Authors:  J H Cox; B C Knight; J Ivanyi
Journal:  Infect Immun       Date:  1989-06       Impact factor: 3.441

3.  Quantitative analysis of T cell homeostatic proliferation.

Authors:  Cheng-Rui Li; Sharon Santoso; David D Lo
Journal:  Cell Immunol       Date:  2008-03-03       Impact factor: 4.868

4.  Interaction of Mycobacterium avium with human monocyte-derived dendritic cells.

Authors:  N Mohagheghpour; A van Vollenhoven; J Goodman; L E Bermudez
Journal:  Infect Immun       Date:  2000-10       Impact factor: 3.441

5.  Dendritic cells stimulate primary human cytolytic lymphocyte responses in the absence of CD4+ helper T cells.

Authors:  J W Young; R M Steinman
Journal:  J Exp Med       Date:  1990-04-01       Impact factor: 14.307

6.  Activity of CD4+ T-cell clones of type 1 and type 2 in generation of influenza virus-specific cytotoxic responses in vitro.

Authors:  G Palladino; P A Scherle; W Gerhard
Journal:  J Virol       Date:  1991-11       Impact factor: 5.103

7.  Cellular autoimmunity to retinal specific antigens in patients with Behçet's disease.

Authors:  J H Yamamoto; M Minami; G Inaba; K Masuda; M Mochizuki
Journal:  Br J Ophthalmol       Date:  1993-09       Impact factor: 4.638

8.  Antigen-presenting characteristics of peritoneal cells of Salmonella enteritidis 11RX-infected mice.

Authors:  M Pope; I Kotlarski
Journal:  Immunology       Date:  1992-10       Impact factor: 7.397

9.  Graft-versus-host disease after brown Norway-to-Lewis and Lewis-to-Brown Norway rat intestinal transplantation under FK506.

Authors:  N Murase; A J Demetris; J Woo; M Tanabe; T Furuya; S Todo; T E Starzl
Journal:  Transplantation       Date:  1993-01       Impact factor: 4.939

10.  Microglial cells qualify as the stimulators of unprimed CD4+ and CD8+ T lymphocytes in the central nervous system.

Authors:  E Cash; O Rott
Journal:  Clin Exp Immunol       Date:  1994-11       Impact factor: 4.330

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