Literature DB >> 25265649

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Deep Dutta, Indira Maisnam, Ankit Shrivastava, Anirban Sinha, Sujoy Ghosh, Pradip Mukhopadhyay, Satinath Mukhopadhyay, Subhankar Chowdhury.   

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Year:  2014        PMID: 25265649      PMCID: PMC4165015     

Source DB:  PubMed          Journal:  Indian J Med Res        ISSN: 0971-5916            Impact factor:   2.375


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Sir, The authors appreciate the comments of the esteemed reader of our article1. The authors agree with the observation that the occurrence of vitamin-D deficiency/insufficiency of 73.5 per cent (115/157) among individuals with prediabetes in our study was reflective of the widespread vitamin-D deficiency in the general population. The same has already been mentioned in the summary of the article in the last paragraph of the discussion section. The primary objective of this cross-sectional study was not to evaluate the burden of vitamin-D deficiency/insufficiency in prediabetes, but to highlight the inverse correlation between vitamin-D and insulin resistance, even after adjusting for body mass index and glycated haemoglobin. In a subsequent prospective study, we have observed vitamin-D to be predictive of prediabetes reversal to normoglycaemia2. Further, in the first open labelled randomized controlled trial from India, we observed vitamin-D supplementation to be beneficial in improving glycaemic outcomes in prediabetes and it was associated with improvement in insulin resistance, inflammatory cytokines and lipids3.
  3 in total

1.  Urinary albumin : creatinine ratio predicts prediabetes progression to diabetes and reversal to normoglycemia: role of associated insulin resistance, inflammatory cytokines and low vitamin D.

Authors:  Deep Dutta; Subhadip Choudhuri; Samim Ali Mondal; Satinath Mukherjee; Subhankar Chowdhury
Journal:  J Diabetes       Date:  2013-12-17       Impact factor: 4.006

2.  Vitamin-D supplementation in prediabetes reduced progression to type 2 diabetes and was associated with decreased insulin resistance and systemic inflammation: an open label randomized prospective study from Eastern India.

Authors:  Deep Dutta; Samim Ali Mondal; Subhadip Choudhuri; Indira Maisnam; Abu Hena Hasanoor Reza; Basudeb Bhattacharya; Subhankar Chowdhury; Satinath Mukhopadhyay
Journal:  Diabetes Res Clin Pract       Date:  2014-01-06       Impact factor: 5.602

3.  Serum vitamin-D predicts insulin resistance in individuals with prediabetes.

Authors:  Deep Dutta; Indira Maisnam; Ankit Shrivastava; Anirban Sinha; Sujoy Ghosh; Pradip Mukhopadhyay; Satinath Mukhopadhyay; Subhankar Chowdhury
Journal:  Indian J Med Res       Date:  2013-12       Impact factor: 2.375

  3 in total

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