Literature DB >> 2526507

Prostaglandin A and J: antitumor and antiviral prostaglandins.

M Fukushima1, T Kato, S Narumiya, Y Mizushima, H Sasaki, Y Terashima, Y Nishiyama, M G Santoro.   

Abstract

Prostaglandin(PG)s of the A and J series are categorized as antitumor, antiviral PGs. They have a reactive alpha, beta-unsaturated carbonyl in the cyclopentenone ring, which could be the active moiety. They are actively incorporated into cells and in part transferred to the nuclei, and lead to cell cycle arrest at G1 or cell death depending on the dose.

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Year:  1989        PMID： 2526507

Source DB:  PubMed          Journal:  Adv Prostaglandin Thromboxane Leukot Res        ISSN： 0732-8141


  8 in total

1.  Targeting of histone acetyltransferase p300 by cyclopentenone prostaglandin Δ(12)-PGJ(2) through covalent binding to Cys(1438).

Authors:  Kodihalli C Ravindra; Vivek Narayan; Gerald H Lushington; Blake R Peterson; K Sandeep Prabhu
Journal:  Chem Res Toxicol       Date:  2011-12-16       Impact factor: 3.739

2.  Prostaglandins with antiproliferative activity induce the synthesis of a heat shock protein in human cells.

Authors:  M G Santoro; E Garaci; C Amici
Journal:  Proc Natl Acad Sci U S A       Date:  1989-11       Impact factor: 11.205

3.  PLIP, a novel splice variant of Tip60, interacts with group IV cytosolic phospholipase A(2), induces apoptosis, and potentiates prostaglandin production.

Authors:  A M Sheridan; T Force; H J Yoon; E O'Leary; G Choukroun; M R Taheri; J V Bonventre
Journal:  Mol Cell Biol       Date:  2001-07       Impact factor: 4.272

4.  Preferential binding of growth inhibitory prostaglandins by the target protein of a carcinogen.

Authors:  S H Khan; S Sorof
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

5.  Induction of HSP70 gene expression by the antiproliferative prostaglandin PGA2: a growth-dependent response mediated by activation of heat shock transcription factor.

Authors:  N J Holbrook; S G Carlson; A M Choi; J Fargnoli
Journal:  Mol Cell Biol       Date:  1992-04       Impact factor: 4.272

Review 6.  Preclinical studies of antitumor prostaglandins by using human ovarian cancer cells.

Authors:  Y Kikuchi; T Kita; J Hirata; M Fukushima
Journal:  Cancer Metastasis Rev       Date:  1994-12       Impact factor: 9.264

7.  Human lung fibroblasts produce proresolving peroxisome proliferator-activated receptor-γ ligands in a cyclooxygenase-2-dependent manner.

Authors:  Shannon H Lacy; Collynn F Woeller; Thomas H Thatcher; Krishna Rao Maddipati; Kenneth V Honn; Patricia J Sime; Richard P Phipps
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2016-09-09       Impact factor: 5.464

8.  15d-PGJ2 induces apoptosis of mouse oligodendrocyte precursor cells.

Authors:  Zhongmin Xiang; Tong Lin; Steven A Reeves
Journal:  J Neuroinflammation       Date:  2007-07-16       Impact factor: 8.322
  8 in total

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