Literature DB >> 25264962

Electrochemically driven drug metabolism via a CYP1A2-UGT1A10 bienzyme confined in a graphene nano-cage.

Jusheng Lu1, Yuanjian Zhang, Henan Li, Jiachao Yu, Songqin Liu.   

Abstract

A graphene nano-cage with regulatable space for the assembly of a cytochrome P450 1A2-UDP-glucuronosyltransferase 1A10 bienzyme complex has been constructed via a click reaction, and successfully used to study drug sequential metabolism using an electrochemically-driven method.

Entities:  

Mesh:

Substances:

Year:  2014        PMID: 25264962     DOI: 10.1039/c4cc06200k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

Review 1.  Engineering cytochrome P450 enzyme systems for biomedical and biotechnological applications.

Authors:  Zhong Li; Yuanyuan Jiang; F Peter Guengerich; Li Ma; Shengying Li; Wei Zhang
Journal:  J Biol Chem       Date:  2019-12-06       Impact factor: 5.157

2.  Molecular machine and gold/graphene quantum dot hybrid based dual amplification strategy for voltammetric detection of VEGF165.

Authors:  Chu Hongxia; Li Zaijun; Li Ruiyi; Wang Guangli; Gu Zhiguo
Journal:  Mikrochim Acta       Date:  2019-03-15       Impact factor: 5.833

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.