AIMS: to validate the PROFUND index in PP in Primary Health Care (PHC). DESIGN: two-year prospective multicenter study. LOCATION: three health care centers in Seville Province (Spain). SUBJECTS OF THE ASSESSMENT: PP with signed informed consent. SAMPLE: n=446 (p=20%; α=5%; β=99%); consecutive sampling. MEASUREMENT: Dependent variable: mortality (2 years). INDEPENDENT VARIABLES: socio-demography, clinic, anthropometric, laboratory, pharmacologic prescriptions, functional, cognitive and socio-familiar evaluation and the use of health resources. INFORMATION SOURCE: interview with patients and clinical charts. STATISTICAL ANALYSIS: uni and multivariate analysis according to the variables; Accuracy was assessed in the cohort by risk terciles calibration, and discrimination power, by ROC curves. Finally, accuracy of the index was compared with that of the Charlson index. RESULTS: 446 subjects were included (53.8% men); average age was 75.44yr (Confidence interval 95% 74.58-76.31). Average of diagnostic categories was 2.37 (Confidence interval 95% 2.30-2.44). Prevalent categories were: A (64.1%), F (41.7%) and E (33.5%). Mortality within 2 years was 24.1%. Calibration in predicted/observed mortality along the three established risk strata was 16%/16.7% for PP with 0-2 points, 22%/19.5% for PP with 3-6, and 34%/36% for PP with 7 or more points (Hosmer-Lemeshow test with p=0.119). Discrimination power of PHC PROFUND's by area under the curve was (AUC) ROC was 0.622 (Confidence interval 95% 0.556-0.689; p<0.001), and that of Charlson index 0.510 (Confidence interval 95% 0.446 - 0.575; p>0.005). CONCLUSIONS: The PROFUND index is a good indicative tool in the stratification of 2-year mortality risk polypathological patients in PHC.
AIMS: to validate the PROFUND index in PP in Primary Health Care (PHC). DESIGN: two-year prospective multicenter study. LOCATION: three health care centers in Seville Province (Spain). SUBJECTS OF THE ASSESSMENT: PP with signed informed consent. SAMPLE: n=446 (p=20%; α=5%; β=99%); consecutive sampling. MEASUREMENT: Dependent variable: mortality (2 years). INDEPENDENT VARIABLES: socio-demography, clinic, anthropometric, laboratory, pharmacologic prescriptions, functional, cognitive and socio-familiar evaluation and the use of health resources. INFORMATION SOURCE: interview with patients and clinical charts. STATISTICAL ANALYSIS: uni and multivariate analysis according to the variables; Accuracy was assessed in the cohort by risk terciles calibration, and discrimination power, by ROC curves. Finally, accuracy of the index was compared with that of the Charlson index. RESULTS: 446 subjects were included (53.8% men); average age was 75.44yr (Confidence interval 95% 74.58-76.31). Average of diagnostic categories was 2.37 (Confidence interval 95% 2.30-2.44). Prevalent categories were: A (64.1%), F (41.7%) and E (33.5%). Mortality within 2 years was 24.1%. Calibration in predicted/observed mortality along the three established risk strata was 16%/16.7% for PP with 0-2 points, 22%/19.5% for PP with 3-6, and 34%/36% for PP with 7 or more points (Hosmer-Lemeshow test with p=0.119). Discrimination power of PHC PROFUND's by area under the curve was (AUC) ROC was 0.622 (Confidence interval 95% 0.556-0.689; p<0.001), and that of Charlson index 0.510 (Confidence interval 95% 0.446 - 0.575; p>0.005). CONCLUSIONS: The PROFUND index is a good indicative tool in the stratification of 2-year mortality risk polypathological patients in PHC.
Authors: Manuel Méndez-Bailon; Rosario Iguarán-Bermudez; Francesc Formiga-Pérez; José Carlos Arévalo Lorido; Iván Suárez-Pedreira; Jose Luis Morales-Rull; Ana Serrado-Iglesias; Pau Llacer-Iborra; Gabriela Ormaechea-Gorricho; Francisco Javier Carrasco-Sánchez; Jesús Casado-Cerrada; Emmanuel Andrès; Jesús Diez-Manglano; Noel Lorenzo-Villalba; Manuel Montero-Pérez-Barquero Journal: J Clin Med Date: 2022-03-28 Impact factor: 4.241
Authors: Marta Morales-Puerto; María Ruiz-Díaz; Marta Aranda-Gallardo; José Miguel Morales-Asencio; Purificación Alcalá-Gutiérrez; José Antonio Rodríguez-Montalvo; Álvaro León-Campos; Silvia García-Mayor; José Carlos Canca-Sánchez Journal: Int J Environ Res Public Health Date: 2022-07-14 Impact factor: 4.614
Authors: Valle Coronado-Vázquez; Carlota Canet-Fajas; María Valle Ramírez-Durán; Juan Gómez-Salgado; José Miguel Robles-Romero; Javier Fagundo-Rivera; Macarena Romero-Martín Journal: Healthcare (Basel) Date: 2020-06-11
Authors: M Bernabeu-Wittel; J E Ternero-Vega; P Díaz-Jiménez; C Conde-Guzmán; M D Nieto-Martín; L Moreno-Gaviño; J Delgado-Cuesta; M Rincón-Gómez; L Giménez-Miranda; M D Navarro-Amuedo; M M Muñoz-García; S Calzón-Fernández; M Ollero-Baturone Journal: Arch Gerontol Geriatr Date: 2020-08-25 Impact factor: 4.163