Literature DB >> 25261555

Gluconeogenesis in cancer: door wide open.

Katharina Leithner1, Andelko Hrzenjak2, Horst Olschewski3.   

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Year:  2014        PMID: 25261555      PMCID: PMC4210322          DOI: 10.1073/pnas.1415680111

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


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  5 in total

Review 1.  The mitochondrial isoform of phosphoenolpyruvate carboxykinase (PEPCK-M) and glucose homeostasis: has it been overlooked?

Authors:  Romana Stark; Richard G Kibbey
Journal:  Biochim Biophys Acta       Date:  2013-10-28

Review 2.  How cancer metabolism is tuned for proliferation and vulnerable to disruption.

Authors:  Almut Schulze; Adrian L Harris
Journal:  Nature       Date:  2012-11-15       Impact factor: 49.962

3.  Tumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusion.

Authors:  Ping Zhang; Bo Tu; Hua Wang; Ziyang Cao; Ming Tang; Chaohua Zhang; Bo Gu; Zhiming Li; Lina Wang; Yang Yang; Ying Zhao; Haiying Wang; Jianyuan Luo; Chu-Xia Deng; Bin Gao; Robert G Roeder; Wei-Guo Zhu
Journal:  Proc Natl Acad Sci U S A       Date:  2014-07-09       Impact factor: 11.205

4.  Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) is a pro-survival, endoplasmic reticulum (ER) stress response gene involved in tumor cell adaptation to nutrient availability.

Authors:  Andrés Méndez-Lucas; Petra Hyroššová; Laura Novellasdemunt; Francesc Viñals; Jose C Perales
Journal:  J Biol Chem       Date:  2014-06-27       Impact factor: 5.157

5.  PCK2 activation mediates an adaptive response to glucose depletion in lung cancer.

Authors:  K Leithner; A Hrzenjak; M Trötzmüller; T Moustafa; H C Köfeler; C Wohlkoenig; E Stacher; J Lindenmann; A L Harris; A Olschewski; H Olschewski
Journal:  Oncogene       Date:  2014-03-17       Impact factor: 9.867

  5 in total
  4 in total

1.  PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity.

Authors:  Joao Incio; Josh Tam; Nuh N Rahbari; Priya Suboj; Dan T McManus; Shan M Chin; Trupti D Vardam; Ana Batista; Suboj Babykutty; Keehoon Jung; Anna Khachatryan; Tai Hato; Jennifer A Ligibel; Ian E Krop; Stefan B Puchner; Christopher L Schlett; Udo Hoffmman; Marek Ancukiewicz; Masabumi Shibuya; Peter Carmeliet; Raquel Soares; Dan G Duda; Rakesh K Jain; Dai Fukumura
Journal:  Clin Cancer Res       Date:  2016-02-09       Impact factor: 12.531

2.  Reply to Leithner et al.: Focus on phopshoenolpyruvate carboxykinase (PEPCK): a target of the p53-SIRT6-FoxO1 axis.

Authors:  Zhiming Li; Wei-Guo Zhu
Journal:  Proc Natl Acad Sci U S A       Date:  2014-09-26       Impact factor: 11.205

3.  Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation.

Authors:  Xue-Li Bian; Hang-Zi Chen; Peng-Bo Yang; Ying-Ping Li; Fen-Na Zhang; Jia-Yuan Zhang; Wei-Jia Wang; Wen-Xiu Zhao; Sheng Zhang; Qi-Tao Chen; Yu Zheng; Xiao-Yu Sun; Xiao-Min Wang; Kun-Yi Chien; Qiao Wu
Journal:  Nat Commun       Date:  2017-02-27       Impact factor: 14.919

4.  Inhibition of glutamate oxaloacetate transaminase 1 in cancer cell lines results in altered metabolism with increased dependency of glucose.

Authors:  Xiaoshan Zhou; Sophie Curbo; Fuqiang Li; Shuba Krishnan; Anna Karlsson
Journal:  BMC Cancer       Date:  2018-05-11       Impact factor: 4.430

  4 in total

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