Literature DB >> 2526103

The intraocular pressure response of human atrial natriuretic factor in glaucoma.

M Diestelhorst1, G K Krieglstein.   

Abstract

In an open label, single dose study on ten glaucoma patients with bilateral untreated IOP levels exceeding 30 mmHg the effects of 100 micrograms human atrial natriuretic factor (HANF) on IOP, systolic blood pressure, pulse rate and serum electrolytes were investigated. The intravenous application of HANF decreased IOP over more than 8 hrs. The magnitude of IOP reduction in this study was in the range of 4-7 mmHg. There was no significant change in blood pressure, pulse rate or serum electrolytes. The verified, yet still limited efficacy of HANF on IOP in glaucoma warrants further investigations.

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Year:  1989        PMID： 2526103     DOI： 10.1007/bf02028647

Source DB:  PubMed          Journal:  Int Ophthalmol        ISSN： 0165-5701            Impact factor:   2.031


  7 in total

1.  Localization and characterization of specific receptors for atrial natriuretic factor in the ciliary processes of the eye.

Authors:  C Bianchi; M B Anand-Srivastava; A De Léan; J Gutkowska; D Forthomme; J Genest; M Cantin
Journal:  Curr Eye Res       Date:  1986-04       Impact factor: 2.424

Review 2.  Atriopeptin: a cardiac hormone intimately involved in fluid, electrolyte, and blood-pressure homeostasis.

Authors:  P Needleman; J E Greenwald
Journal:  N Engl J Med       Date:  1986-03-27       Impact factor: 91.245

3.  Synthetic atrial natriuretic factor lowers rabbit intraocular pressure.

Authors:  M F Sugrue; M P Viader
Journal:  Eur J Pharmacol       Date:  1986-11-04       Impact factor: 4.432

Review 4.  [Atrial natriuretic factor. Endocrine function of the heart].

Authors:  R M Arendt; A L Gerbes
Journal:  Dtsch Med Wochenschr       Date:  1986-11-28       Impact factor: 0.628

Review 5.  Pharmacologic effects of atrial natriuretic peptide.

Authors:  R J Winquist
Journal:  Endocrinol Metab Clin North Am       Date:  1987-03       Impact factor: 4.741

6.  Atriopeptin-activated guanylate cyclase in the anterior segment. Identification, localization, and effects of atriopeptins on IOP.

Authors:  J A Nathanson
Journal:  Invest Ophthalmol Vis Sci       Date:  1987-08       Impact factor: 4.799

7.  Atrial natriuretic hormones--thirty years after the discovery of atrial volume receptors.

Authors:  H J Kramer; B Lichardus
Journal:  Klin Wochenschr       Date:  1986-08-15
  7 in total
  6 in total

1.  Atriopeptin, sodium azide and cyclic GMP reduce secretion of aqueous humour and inhibit intracellular calcium release in bovine cultured ciliary epithelium.

Authors:  M Shahidullah; W S Wilson
Journal:  Br J Pharmacol       Date:  1999-07       Impact factor: 8.739

2.  Mapping of a gene for autosomal dominant juvenile-onset open-angle glaucoma to chromosome Iq.

Authors:  J E Richards; P R Lichter; M Boehnke; J L Uro; D Torrez; D Wong; A T Johnson
Journal:  Am J Hum Genet       Date:  1994-01       Impact factor: 11.025

3.  Differential regulation of natriuretic peptide receptors on ciliary body epithelial cells.

Authors:  R B Crook; A T Chang
Journal:  Biochem J       Date:  1997-05-15       Impact factor: 3.857

4.  The effect of isosorbide-mononitrate eye drops on the human intraocular pressure and aqueous humor dynamics.

Authors:  M Diestelhorst; B Hinzpeter; G K Krieglstein
Journal:  Int Ophthalmol       Date:  1991-07       Impact factor: 2.031

5.  Brain natriuretic peptide: identification of a second natriuretic peptide in human aqueous humour.

Authors:  J Salzmann; D Flitcroft; C Bunce; D Gordon; R Wormald; C Migdal
Journal:  Br J Ophthalmol       Date:  1998-07       Impact factor: 4.638

6.  Evidence for a new role of natriuretic peptides: control of intraocular pressure.

Authors:  T J Wolfensberger; D R Singer; T Freegard; N D Markandu; M G Buckley; G A MacGregor
Journal:  Br J Ophthalmol       Date:  1994-06       Impact factor: 4.638
  6 in total

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