| Literature DB >> 25261015 |
Camila Nascimento1, Helena Kyunghee Kim, L Trevor Young, Karina Martinez Mendonça, Lea Tenenholz Grinberg, Beny Lafer, Ana Cristina Andreazza.
Abstract
The aim of this study was to elucidate whether glutathione is involved in lithium's ability to decrease carbonylation and nitration produced by complex I inhibition, which is consistently found in BD. Neuroblastoma cells were treated with rotenone, a complex I inhibitor. Our results suggest that glutathione is essential for lithium's ability to ameliorate rotenone-induced protein carbonylation, but not nitration.Entities:
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Year: 2014 PMID： 25261015 DOI： 10.1007/s00702-014-1318-8
Source DB: PubMed Journal: J Neural Transm (Vienna) ISSN： 0300-9564 Impact factor: 3.575