Literature DB >> 25258668

Human induced pluripotent stem cells: A new source for brown and white adipocytes.

Anne-Laure Hafner1, Christian Dani1.   

Abstract

Mesenchymal stem cells (MSCs) derived from human induced pluripotent stem cells (hiPSCs) provide a novel source for generating adipocytes, thus opening new avenues for fundamental research and clinical medicine. We present the adipogenic potential of hiPSCs and the various methods to derive hiPSC-MSCs. We discuss the main characteristic of hiPSC-MSCs, which is their low adipogenic capacity as compared to adult-MSCs. Finally, we propose several hypotheses to explanation this feature, underlying a potential critical role of the micro-environment. We favour the hypothesis that the range of factors or culture conditions required to induce adipocyte differentiation of MSCs derived from adult tissues and from embryonic-like cells could differ.

Entities:  

Keywords:  Brown adipocytes; Human induced pluripotent stem cells; Lipodystrophy; Mesenchymal stem cells; Obesity; White adipocytes

Year:  2014        PMID： 25258668      PMCID： PMC4172675          DOI： 10.4252/wjsc.v6.i4.467

Source DB:  PubMed          Journal:  World J Stem Cells        ISSN： 1948-0210            Impact factor:   5.326


  37 in total

1.  Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice.

Authors:  O Gavrilova; B Marcus-Samuels; D Graham; J K Kim; G I Shulman; A L Castle; C Vinson; M Eckhaus; M L Reitman
Journal:  J Clin Invest       Date:  2000-02       Impact factor: 14.808

2.  Adipose-derived stromal cells: Their identity and uses in clinical trials, an update.

Authors:  Louis Casteilla; Valérie Planat-Benard; Patrick Laharrague; Béatrice Cousin
Journal:  World J Stem Cells       Date:  2011-04-26       Impact factor: 5.326

3.  Production of functional classical brown adipocytes from human pluripotent stem cells using specific hemopoietin cocktail without gene transfer.

Authors:  Miwako Nishio; Takeshi Yoneshiro; Masako Nakahara; Shinnosuke Suzuki; Koichi Saeki; Mamoru Hasegawa; Yuko Kawai; Hidenori Akutsu; Akihiro Umezawa; Kazuki Yasuda; Kazuyuki Tobe; Akira Yuo; Kazuo Kubota; Masayuki Saito; Kumiko Saeki
Journal:  Cell Metab       Date:  2012-09-05       Impact factor: 27.287

Review 4.  Distribution and development of brown adipocytes in the murine and human adipose organ.

Authors:  Andrea Frontini; Saverio Cinti
Journal:  Cell Metab       Date:  2010-04-07       Impact factor: 27.287

5.  Human embryonic stem cell-derived mesenchymal progenitors--potential in regenerative medicine.

Authors:  Camilla Karlsson; Katarina Emanuelsson; Fredrik Wessberg; Kristina Kajic; Mathilda Zetterström Axell; Peter S Eriksson; Anders Lindahl; Johan Hyllner; Raimund Strehl
Journal:  Stem Cell Res       Date:  2009-05-19       Impact factor: 2.020

6.  Functional comparison of human-induced pluripotent stem cell-derived mesenchymal cells and bone marrow-derived mesenchymal stromal cells from the same donor.

Authors:  Solvig Diederichs; Rocky S Tuan
Journal:  Stem Cells Dev       Date:  2014-04-28       Impact factor: 3.272

7.  Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT).

Authors:  Philippe Bourin; Bruce A Bunnell; Louis Casteilla; Massimo Dominici; Adam J Katz; Keith L March; Heinz Redl; J Peter Rubin; Kotaro Yoshimura; Jeffrey M Gimble
Journal:  Cytotherapy       Date:  2013-04-06       Impact factor: 5.414

8.  Intrinsic differences in adipocyte precursor cells from different white fat depots.

Authors:  Yazmín Macotela; Brice Emanuelli; Marcelo A Mori; Stephane Gesta; Tim J Schulz; Yu-Hua Tseng; C Ronald Kahn
Journal:  Diabetes       Date:  2012-05-17       Impact factor: 9.461

9.  One-step derivation of mesenchymal stem cell (MSC)-like cells from human pluripotent stem cells on a fibrillar collagen coating.

Authors:  Yongxing Liu; A Jon Goldberg; James E Dennis; Gloria A Gronowicz; Liisa T Kuhn
Journal:  PLoS One       Date:  2012-03-21       Impact factor: 3.240

10.  Derivation of multipotent mesenchymal precursors from human embryonic stem cells.

Authors:  Tiziano Barberi; Lucy M Willis; Nicholas D Socci; Lorenz Studer
Journal:  PLoS Med       Date:  2005-06-28       Impact factor: 11.069
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  8 in total

1.  Regulation of Myogenesis by a Na/K-ATPase α1 Caveolin-Binding Motif.

Authors:  Minqi Huang; Xiaoliang Wang; Moumita Banerjee; Shreya T Mukherji; Laura C Kutz; Aijie Zhao; Michael Sepanski; Chen-Ming Fan; Guo-Zhang Zhu; Jiang Tian; Da-Zhi Wang; Hua Zhu; Zi-Jian Xie; Sandrine V Pierre; Liquan Cai
Journal:  Stem Cells       Date:  2022-03-16       Impact factor: 5.845

Review 2.  Opportunities and challenges in three-dimensional brown adipogenesis of stem cells.

Authors:  Andrea M Unser; Yangzi Tian; Yubing Xie
Journal:  Biotechnol Adv       Date:  2015-07-29       Impact factor: 14.227

3.  Brown-like adipose progenitors derived from human induced pluripotent stem cells: Identification of critical pathways governing their adipogenic capacity.

Authors:  Anne-Laure Hafner; Julian Contet; Christophe Ravaud; Xi Yao; Phi Villageois; Kran Suknuntha; Karima Annab; Pascal Peraldi; Bernard Binetruy; Igor I Slukvin; Annie Ladoux; Christian Dani
Journal:  Sci Rep       Date:  2016-08-31       Impact factor: 4.379

4.  Functional Human Beige Adipocytes From Induced Pluripotent Stem Cells.

Authors:  Anne-Claire Guénantin; Nolwenn Briand; Emilie Capel; Florent Dumont; Romain Morichon; Claire Provost; Francesca Stillitano; Dorota Jeziorowska; Jean-Pierre Siffroi; Roger J Hajjar; Bruno Fève; Jean-Sébastien Hulot; Philippe Collas; Jacqueline Capeau; Corinne Vigouroux
Journal:  Diabetes       Date:  2017-03-07       Impact factor: 9.461

Review 5.  Lipodystrophic syndromes due to LMNA mutations: recent developments on biomolecular aspects, pathophysiological hypotheses and therapeutic perspectives.

Authors:  Corinne Vigouroux; Anne-Claire Guénantin; Camille Vatier; Emilie Capel; Caroline Le Dour; Pauline Afonso; Guillaume Bidault; Véronique Béréziat; Olivier Lascols; Jacqueline Capeau; Nolwenn Briand; Isabelle Jéru
Journal:  Nucleus       Date:  2018-01-01       Impact factor: 4.197

6.  Fast Adipogenesis Tracking System (FATS)-a robust, high-throughput, automation-ready adipogenesis quantification technique.

Authors:  Chengxiang Yuan; Smarajit Chakraborty; Krishna Kanth Chitta; Subha Subramanian; Tau En Lim; Weiping Han; K N Bhanu Prakash; Shigeki Sugii
Journal:  Stem Cell Res Ther       Date:  2019-01-22       Impact factor: 6.832

7.  A Renewable Source of Human Beige Adipocytes for Development of Therapies to Treat Metabolic Syndrome.

Authors:  Su Su; Anyonya R Guntur; Daniel C Nguyen; Shameem S Fakory; Chad C Doucette; Cassandra Leech; Humphrey Lotana; Matthew Kelley; Jaspreet Kohli; Julieta Martino; Sunder Sims-Lucas; Lucy Liaw; Calvin Vary; Clifford J Rosen; Aaron C Brown
Journal:  Cell Rep       Date:  2018-12-11       Impact factor: 9.423

Review 8.  Human Pluripotent Stem Cells: A Relevant Model to Identify Pathways Governing Thermogenic Adipocyte Generation.

Authors:  Xi Yao; Vincent Dani; Christian Dani
Journal:  Front Endocrinol (Lausanne)       Date:  2020-01-21       Impact factor: 5.555
  8 in total

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