Literature DB >> 25256940

Fecal diversion for the treatment of fulminant cytomegalovirus colitis: report of a case.

Gamal Mostafa1, Michael Drew Honaker.   

Abstract

Cytomegalovirus (CMV) colitis in the immunosuppressed patient is common and is usually self-limited by treatment consisting of intravenous anti-viral medications. However, in the immunocompetent patient, CMV colitis is extremely rare and is associated with a high mortality rate that approaches 32 % (Galiatsatos et al. in Dig Dis Sci 50:609-616, 2005). We herein present the case of a 45-year-old immunocompetent male who developed fulminant CMV colitis. He was initially started on anti-viral agents but the disease continued to progress. After a surgical consultation was obtained, he underwent diverting loop ileostomy in an attempt to avoid a total abdominal colectomy. He responded well and had successful resolution of his disease. Approximately nine months later, he underwent successful ileostomy takedown. Diversion may be an alternative to total abdominal colectomy for CMV colitis or other causes of fulminant colitis. Given the rare nature of fulminant CMV colitis, further randomized studies will be difficult; however, this does appear to be a treatment option as an alternative to total abdominal colectomy.

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Year:  2014        PMID: 25256940     DOI: 10.1007/s00595-014-1033-y

Source DB:  PubMed          Journal:  Surg Today        ISSN: 0941-1291            Impact factor:   2.549


  4 in total

1.  Life-threatening cytomegalovirus colitis in the immunocompetent patient: report of a case and review of the literature.

Authors:  S Karakozis; E Gongora; M Caceres; E Brun; J W Cook
Journal:  Dis Colon Rectum       Date:  2001-11       Impact factor: 4.585

2.  Diverting loop ileostomy and colonic lavage: an alternative to total abdominal colectomy for the treatment of severe, complicated Clostridium difficile associated disease.

Authors:  Matthew D Neal; John C Alverdy; Daniel E Hall; Richard L Simmons; Brian S Zuckerbraun
Journal:  Ann Surg       Date:  2011-09       Impact factor: 12.969

Review 3.  Meta-analysis of outcome of cytomegalovirus colitis in immunocompetent hosts.

Authors:  Polymnia Galiatsatos; Ian Shrier; Esther Lamoureux; Andrew Szilagyi
Journal:  Dig Dis Sci       Date:  2005-04       Impact factor: 3.199

4.  Cytomegalovirus colitis in AIDS: presentation in 44 patients and a review of the literature.

Authors:  D T Dieterich; M Rahmin
Journal:  J Acquir Immune Defic Syndr (1988)       Date:  1991
  4 in total

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