Literature DB >> 25256780

Gestational hypoxia and epigenetic programming of brain development disorders.

Qingyi Ma1, Fuxia Xiong1, Lubo Zhang2.   

Abstract

Adverse environmental conditions faced by an individual early during its life, such as gestational hypoxia, can have a profound influence on the risk of diseases, such as neurological disorders, in later life. Clinical and preclinical studies suggest that epigenetic programming of gene expression patterns in response to maternal stress have a crucial role in the fetal origins of neurological diseases. Herein, we summarize recent studies regarding the role of epigenetic mechanisms in the developmental programming of neurological diseases in offspring, primarily focusing on DNA methylation/demethylation and miRNAs. Such information could increase our understanding of the fetal origins of adult diseases and help develop effective prevention and intervention against neurological diseases.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Mesh：

Year:  2014        PMID： 25256780      PMCID： PMC4262616          DOI： 10.1016/j.drudis.2014.09.010

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  180 in total

Review 1.  MicroRNAs: small RNAs with a big role in gene regulation.

Authors:  Lin He; Gregory J Hannon
Journal:  Nat Rev Genet       Date:  2004-07       Impact factor: 53.242

2.  Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly.

Authors:  Shireen A Sarraf; Irina Stancheva
Journal:  Mol Cell       Date:  2004-08-27       Impact factor: 17.970

Review 3.  Epigenetics and the nervous system.

Authors:  Mark F Mehler
Journal:  Ann Neurol       Date:  2008-12       Impact factor: 10.422

4.  Norepinephrine causes epigenetic repression of PKCε gene in rodent hearts by activating Nox1-dependent reactive oxygen species production.

Authors:  Fuxia Xiong; Daliao Xiao; Lubo Zhang
Journal:  FASEB J       Date:  2012-03-21       Impact factor: 5.191

Review 5.  Fetal nutrition and cardiovascular disease in adult life.

Authors:  D J Barker; P D Gluckman; K M Godfrey; J E Harding; J A Owens; J S Robinson
Journal:  Lancet       Date:  1993-04-10       Impact factor: 79.321

6.  Magnesium sulfate protection of fetal rat brain from severe maternal hypoxia.

Authors:  M Hallak; J W Hotra; W J Kupsky
Journal:  Obstet Gynecol       Date:  2000-07       Impact factor: 7.661

7.  miR-210 suppresses BNIP3 to protect against the apoptosis of neural progenitor cells.

Authors:  Fei Wang; Lei Xiong; Xin Huang; Tong Zhao; Li-ying Wu; Zhao-hui Liu; Xuefeng Ding; Shuhong Liu; Yan Wu; Yongqi Zhao; Kuiwu Wu; Ling-ling Zhu; Ming Fan
Journal:  Stem Cell Res       Date:  2013-04-15       Impact factor: 2.020

8.  Induction of DNA hypomethylation by tumor hypoxia.

Authors:  Siranoush Shahrzad; Kelsey Bertrand; Kanwal Minhas; Brenda L Coomber
Journal:  Epigenetics       Date:  2007-06-14       Impact factor: 4.528

9.  Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer.

Authors:  U Lehmann; B Hasemeier; M Christgen; M Müller; D Römermann; F Länger; H Kreipe
Journal:  J Pathol       Date:  2008-01       Impact factor: 7.996

10.  Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome.

Authors:  Dana C Dolinoy; Jennifer R Weidman; Robert A Waterland; Randy L Jirtle
Journal:  Environ Health Perspect       Date:  2006-04       Impact factor: 9.031
View more
  8 in total

1.  Fetal stress-mediated hypomethylation increases the brain susceptibility to hypoxic-ischemic injury in neonatal rats.

Authors:  Yong Li; Qingyi Ma; Shina Halavi; Katherine Concepcion; Richard E Hartman; Andre Obenaus; Daliao Xiao; Lubo Zhang
Journal:  Exp Neurol       Date:  2015-10-24       Impact factor: 5.330

2.  Whole Genome DNA Methylation Analysis of Obstructive Sleep Apnea: IL1R2, NPR2, AR, SP140 Methylation and Clinical Phenotype.

Authors:  Yung-Che Chen; Ting-Wen Chen; Mao-Chang Su; Chung-Jen Chen; Kuang-Den Chen; Chia-Wei Liou; Petrus Tang; Ting-Ya Wang; Jen-Chieh Chang; Chin-Chou Wang; Hsin-Ching Lin; Chien-Hung Chin; Kuo-Tung Huang; Meng-Chih Lin; Chang-Chun Hsiao
Journal:  Sleep       Date:  2016-04-01       Impact factor: 5.849

Review 3.  Gestational Hypoxia and Developmental Plasticity.

Authors:  Charles A Ducsay; Ravi Goyal; William J Pearce; Sean Wilson; Xiang-Qun Hu; Lubo Zhang
Journal:  Physiol Rev       Date:  2018-07-01       Impact factor: 37.312

4.  Effect of hypoxia on the retina and superior colliculus of neonatal pigs.

Authors:  Noelia Ruzafa; Carmen Rey-Santano; Victoria Mielgo; Xandra Pereiro; Elena Vecino
Journal:  PLoS One       Date:  2017-04-13       Impact factor: 3.240

5.  Aberrant DNA methylation of the toll-like receptors 2 and 6 genes in patients with obstructive sleep apnea.

Authors:  Kuo-Tung Huang; Yung-Che Chen; Chia-Cheng Tseng; Huang-Chih Chang; Mao-Chang Su; Ting-Ya Wang; Yong-Yong Lin; Yi-Xin Zheng; Jen-Chieh Chang; Chien-Hung Chin; Chang-Chun Hsiao; Meng-Chih Lin
Journal:  PLoS One       Date:  2020-02-18       Impact factor: 3.240

6.  Antenatal Hypoxia Accelerates the Onset of Alzheimer's Disease Pathology in 5xFAD Mouse Model.

Authors:  Guofang Shen; Shirley Hu; Zhen Zhao; Lubo Zhang; Qingyi Ma
Journal:  Front Aging Neurosci       Date:  2020-08-21       Impact factor: 5.702

7.  Patterns of gene expression and DNA methylation in human fetal and adult liver.

Authors:  Susan M Huse; Philip A Gruppuso; Kim Boekelheide; Jennifer A Sanders
Journal:  BMC Genomics       Date:  2015-11-21       Impact factor: 3.969

8.  Differential DNA methylation at birth associated with mental disorder in individuals with 22q11.2 deletion syndrome.

Authors:  A Starnawska; C S Hansen; T Sparsø; W Mazin; L Olsen; M Bertalan; A Buil; J Bybjerg-Grauholm; M Bækvad-Hansen; D M Hougaard; P B Mortensen; C B Pedersen; M Nyegaard; T Werge; S Weinsheimer
Journal:  Transl Psychiatry       Date:  2017-08-29       Impact factor: 6.222
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.